| dc.contributor.author | Hervieu, A | |
| dc.contributor.author | Kermorgant, S | |
| dc.date.accessioned | 2021-04-09T15:32:36Z | |
| dc.date.available | 2021-04-09T15:32:36Z | |
| dc.date.issued | 2020-08-18 | |
| dc.identifier.issn | 2372-3556 | |
| dc.identifier.uri | https://qmro.qmul.ac.uk/xmlui/handle/123456789/71155 | |
| dc.description.abstract | We reported that RAC1 is a master regulator of cell migration and anchorage-independent growth, downstream of the oncogenic Receptor Tyrosine Kinase (RTK) MET. RAC1 growth-promoting role is guanosine triphosphatase (GTPase)- and phosphatidylinositol 3-kinase (PI3K)-independent but promotes mammalian target of rapamycin (mTOR) signaling through triggering its plasma membrane localization. | en_US |
| dc.format.extent | 1803029 - ? | |
| dc.language | eng | |
| dc.relation.ispartof | Mol Cell Oncol | |
| dc.subject | MET | en_US |
| dc.subject | PI3K | en_US |
| dc.subject | RAC1 | en_US |
| dc.subject | mTOR | en_US |
| dc.title | Unconventional role of RAC1 in MET-driven anchorage-independent tumor growth. | en_US |
| dc.type | Article | en_US |
| dc.identifier.doi | 10.1080/23723556.2020.1803029 | |
| pubs.author-url | https://www.ncbi.nlm.nih.gov/pubmed/33235904 | en_US |
| pubs.issue | 6 | en_US |
| pubs.notes | Not known | en_US |
| pubs.publication-status | Published online | en_US |
| pubs.volume | 7 | en_US |
| qmul.funder | Unravelling c-Met signalling from autophagic endomembranes::Medical Research Council | en_US |
