Search
Now showing items 31-40 of 115
Solid-state NMR structure of a pathogenic fibril of full-length human alpha-synuclein
(Nature Publishing Group, 2016-03-28)
Misfolded a-synuclein amyloid fibrils are the principal components of Lewy bodies and neurites, hallmarks of Parkinson’s disease
(PD). We present a high-resolution structure of an a-synuclein fibril, in a form that induces ...
Efficacy of a novel, protein-based pneumococcal vaccine against nasopharyngeal carriage of Streptococcus pneumoniae in infants: A phase 2, randomized, controlled, observer-blind study
(Elsevier Ltd., 2017-05-02)
Background
Conserved pneumococcal proteins are potential candidates for inclusion in vaccines against pneumococcal diseases. In the first part of a two-part study, an investigational vaccine (PHiD-CV/dPly/PhtD-30) containing ...