Browsing Biology by Subject "Parkinson's disease"
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Solid-state NMR structure of a pathogenic fibril of full-length human alpha-synuclein
(Nature Publishing Group, 2016-03-28)Misfolded a-synuclein amyloid fibrils are the principal components of Lewy bodies and neurites, hallmarks of Parkinson’s disease (PD). We present a high-resolution structure of an a-synuclein fibril, in a form that induces ...