Browsing Biology by Author "Zhang, L"
Now showing items 1-3 of 3
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A KLK6 Activity-Based Probe Reveals a Role for KLK6 Activity in Pancreatic Cancer Cell Invasion.
Zhang, L; Lovell, S; De Vita, E; Jagtap, PKA; Lucy, D; Goya Grocin, A; Kjær, S; Borg, A; Hennig, J; Miller, AK (2022-12-14)Pancreatic cancer has the lowest survival rate of all common cancers due to late diagnosis and limited treatment options. Serine hydrolases are known to mediate cancer progression and metastasis through initiation of ... -
Light-mediated multi-target protein degradation using arylazopyrazole photoswitchable PROTACs (AP-PROTACs)
Zhang, Q; Kounde, CS; Mondal, M; Greenfield, JL; Baker, JR; Kotelnikov, S; Ignatov, M; Tinworth, CP; Zhang, L; Conole, D (Royal Society of Chemistry (RSC), 2022-09-29) -
A Suite of Activity-Based Probes To Dissect the KLK Activome in Drug-Resistant Prostate Cancer
Lovell, S; Zhang, L; Kryza, T; Neodo, A; Bock, N; De Vita, E; Williams, ED; Engelsberger, E; Xu, C; Bakker, AT (American Chemical Society (ACS), 2021-06-16)