Browsing Biology by Author "Tate, EW"
Now showing items 1-7 of 7
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Beyond targeted protein degradation: LD·ATTECs clear cellular lipid droplets
De Vita, E; Lucy, D; Tate, EW (Springer Science and Business Media LLC, 2021-09) -
Depsipeptides Featuring a Neutral P1 Are Potent Inhibitors of Kallikrein-Related Peptidase 6 with On-Target Cellular Activity
De Vita, E; Schüler, P; Lovell, S; Lohbeck, J; Kullmann, S; Rabinovich, E; Sananes, A; Heßling, B; Hamon, V; Papo, N (American Chemical Society (ACS), 2018-10-11) -
Identification of the first structurally validated covalent ligands of the small GTPase RAB27A
Jamshidiha, M; Lanyon-Hogg, T; Sutherell, CL; Craven, GB; Tersa, M; De Vita, E; Brustur, D; Pérez-Dorado, I; Hassan, S; Petracca, R (Royal Society of Chemistry (RSC), 2022-02-23) -
A KLK6 Activity-Based Probe Reveals a Role for KLK6 Activity in Pancreatic Cancer Cell Invasion.
Zhang, L; Lovell, S; De Vita, E; Jagtap, PKA; Lucy, D; Goya Grocin, A; Kjær, S; Borg, A; Hennig, J; Miller, AK (2022-12-14)Pancreatic cancer has the lowest survival rate of all common cancers due to late diagnosis and limited treatment options. Serine hydrolases are known to mediate cancer progression and metastasis through initiation of ... -
Light-mediated multi-target protein degradation using arylazopyrazole photoswitchable PROTACs (AP-PROTACs)
Zhang, Q; Kounde, CS; Mondal, M; Greenfield, JL; Baker, JR; Kotelnikov, S; Ignatov, M; Tinworth, CP; Zhang, L; Conole, D (Royal Society of Chemistry (RSC), 2022-09-29) -
The Missing Link between (Un)druggable and Degradable KRAS
De Vita, E; Maneiro, M; Tate, EW (American Chemical Society (ACS), 2020-08-26) -
A Suite of Activity-Based Probes To Dissect the KLK Activome in Drug-Resistant Prostate Cancer
Lovell, S; Zhang, L; Kryza, T; Neodo, A; Bock, N; De Vita, E; Williams, ED; Engelsberger, E; Xu, C; Bakker, AT (American Chemical Society (ACS), 2021-06-16)