Browsing Biology by Author "Sarre, LA"

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    • Annelid methylomes reveal ancestral developmental and aging-associated epigenetic erosion across Bilateria 

      Guynes, K; Sarre, LA; Carrillo-Baltodano, AM; Davies, BE; Xu, L; Liang, Y; Martín-Zamora, FM; Hurd, PJ; de Mendoza, A; Martín-Durán, JM (Springer Science and Business Media LLC, 2024-08-01)
      <jats:title>Abstract</jats:title><jats:sec> <jats:title>Background</jats:title> <jats:p>DNA methylation in the form of 5-methylcytosine (5mC) is the most abundant base modification in animals. However, 5mC levels vary ...

    • DNA methylation enables recurrent endogenization of giant viruses in an animal relative. 

      Sarre, LA; Kim, IV; Ovchinnikov, V; Olivetta, M; Suga, H; Dudin, O; Sebé-Pedrós, A; de Mendoza, A (American Association for the Advancement of Science, 2024-07-12)
      5-Methylcytosine (5mC) is a widespread silencing mechanism that controls genomic parasites. In eukaryotes, 5mC has gained complex roles in gene regulation beyond parasite control, yet 5mC has also been lost in many lineages. ...