Browsing Biology by Author "Murphy, MP"
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Naked mole-rats have distinctive cardiometabolic and genetic adaptations to their underground low-oxygen lifestyles.
Faulkes, CG; Eykyn, TR; Miljkovic, JL; Gilbert, JD; Charles, RL; Prag, HA; Patel, N; Hart, DW; Murphy, MP; Bennett, NC (Nature Research, 2024-03-27)The naked mole-rat Heterocephalus glaber is a eusocial mammal exhibiting extreme longevity (37-year lifespan), extraordinary resistance to hypoxia and absence of cardiovascular disease. To identify the mechanisms behind ... -
Selenoprotein deficiency disorder predisposes to aortic aneurysm formation
Schoenmakers, E; Marelli, F; Jørgensen, HF; Visser, WE; Moran, C; Groeneweg, S; Avalos, C; Jurgens, SJ; Figg, N; Finigan, A<jats:title>Abstract</jats:title><jats:p>Aortic aneurysms, which may dissect or rupture acutely and be lethal, can be a part of multisystem disorders that have a heritable basis. We report four patients with deficiency of ...