Browsing Biology by Author "Kendall, A"

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    • Solid-state NMR structure of a pathogenic fibril of full-length human alpha-synuclein 

      Tuttle, MD; Comellas, G; Nieuwkoop, AJ; Covell, DJ; Berthold, DA; Kloepper, KD; Courtney, JM; Kim, JK; Barclay, AM; Kendall, A (Nature Publishing Group, 2016-03-28)
      Misfolded a-synuclein amyloid fibrils are the principal components of Lewy bodies and neurites, hallmarks of Parkinson’s disease (PD). We present a high-resolution structure of an a-synuclein fibril, in a form that induces ...