Browsing Centre for Neuroscience, Surgery and Trauma by Subject "Brain Chemistry"

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    • Characterizing the RNA targets and position-dependent splicing regulation by TDP-43 

      Tollervey, JR; Curk, T; Rogelj, B; Briese, M; Cereda, M; Kayikci, M; König, J; Hortobágyi, T; Nishimura, AL; Zupunski, V (Nature Research, 2011-02-27)
      TDP-43 is a predominantly nuclear RNA-binding protein that forms inclusion bodies in frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS). The mRNA targets of TDP-43 in the human brain and its ...