Browsing Centre for Neuroscience, Surgery and Trauma by Subject "3Rs"
Now showing items 1-2 of 2
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Rethinking animal models of sepsis - working towards improved clinical translation whilst integrating the 3Rs.
(2020-07-17)Sepsis is a major worldwide healthcare issue with unmet clinical need. Despite extensive animal research in this area, successful clinical translation has been largely unsuccessful. We propose one reason for this is that, ... -
Studies on long term behavioural changes in group-housed rat models of brain and spinal cord injury using an automated home cage recording system.
(2019-06-01)BACKGROUND: Neurotrauma patients face major neurological sequelae. The failure in the preclinical-to-clinical translation of candidate therapies could be due to poor evaluation of rodent behaviours after neurotrauma. NEW ...