Browsing Centre for Neuroscience, Surgery and Trauma by Subject "2-Naphthoic acid"
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Investigation of the structural requirements for N-methyl-D-aspartate receptor positive and negative allosteric modulators based on 2-naphthoic acid. (Elsevier/Science Direct, 2018-12-28)The N-methyl-D-aspartate receptor (NMDAR), a ligand-gated ion channel activated by L-glutamate and glycine, plays a major role in the synaptic plasticity underlying learning and memory. NMDARs are involved in neurodegenerative ...