Browsing Centre for Neuroscience, Surgery and Trauma by Subject "multiple sclerosis"
Now showing items 21-39 of 39
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Increased expression of colony-stimulating factor-1 in mouse spinal cord with experimental autoimmune encephalomyelitis correlates with microglial activation and neuronal loss.
(2018-10)Microglia contribute to pathophysiology at all stages of multiple sclerosis. Colony-stimulating factor-1 (CSF1) is crucial for microglial proliferation and activation. In this study we measured the CSF1 levels and studied ... -
Magnetic resonance imaging correlates of neuro-axonal pathology in the MS spinal cord.
(2018-09)In people with multiple sclerosis (MS), the spinal cord is the structure most commonly affected by clinically detectable pathology at presentation, and a key part of the central nervous system involved in chronic disease ... -
Neuromyelitis optica spectrum disorder presenting as rhomboencephalitis.
(2018-05-23)Rhomboencephalitis, at least in its acute phase, is often a severely disabling syndrome, and can be life threatening. A range of underlying conditions can lead to this clinical syndrome. Rapid diagnosis to initiate treatment ... -
Patient-reported outcomes in multiple sclerosis: a prospective registry cohort study.
(2023)Registries have the potential to tackle some of the current limitations in determining the long-term impact of multiple sclerosis. Online assessments using patient-reported outcomes can streamline follow-up enabling ... -
SARS-CoV-2 and Multiple Sclerosis: Not all immune depleting DMTs are equal or bad.
(Wiley Online, 2020-05-08)A major concern during the current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic1 is the use of immunosuppressive therapies for the treatment of multiple sclerosis (MS) due to an increased risk of ... -
Vitamin D supplementation.
(2018-02)Vitamin D testing and supplementation is of great interest to neurologists and their patients. Recommended nutritional intakes of vitamin D in the UK remain focused on bone health, despite increasing evidence for a role ...