Centre for Immunobiology: Recent submissions
Now showing items 561-580 of 1121
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ERO1α promotes hypoxic tumor progression and is associated with poor prognosis in pancreatic cancer.
(2019-10-15)Pancreatic cancer is a leading cause of mortality worldwide due to the difficulty of detecting early-stage disease and our poor understanding of the mediators that drive progression of hypoxic solid tumors. We therefore ... -
Allostasis and the origins of adult-onset diabetes.
(2020-02)Physiological plasticity enables homeostasis to be maintained in biological systems, but when such allostasis fails, then disease can develop. In a new population-based study by Rolandsson et al (https://doi.org/10.1007/ ... -
Extended-spectrum β-lactamase-producing Escherichia coli in human-derived and foodchain-derived samples from England, Wales, and Scotland: an epidemiological surveillance and typing study.
(2019-12)BACKGROUND: Extended-spectrum β-lactamase-producing Escherichia coli isolates (ESBL-E coli) cause more than 5000 cases of bacteraemias annually in the UK. The contribution of the food chain to these infections is debated. ... -
Effects of intermittent IL-2 alone or with peri-cycle antiretroviral therapy in early HIV infection: the STALWART study.
(2010-02-23)BACKGROUND: The Study of Aldesleukin with and without antiretroviral therapy (STALWART) evaluated whether intermittent interleukin-2 (IL-2) alone or with antiretroviral therapy (ART) around IL-2 cycles increased CD4(+) ... -
Teasing Diabetes Apart, One Locus at a Time
(2018-02) -
Genetic Discrimination Between LADA and Childhood-Onset Type 1 Diabetes Within the MHC.
(2020-02)OBJECTIVE: The MHC region harbors the strongest loci for latent autoimmune diabetes in adults (LADA); however, the strength of association is likely attenuated compared with that for childhood-onset type 1 diabetes. In ... -
Flow Cytometry Reveals the Nature of Oncotic Cells
(2019-09-02)