Browsing Centre for Immunobiology by Issue Date
Now showing items 1-20 of 1262
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The circulating methylome in childhood-onset inflammatory bowel disease
(Oxford University Press, 04-10-2024)The genetic contribution to inflammatory bowel disease (IBD) encompassing both Crohn’s disease (CD) and ulcerative colitis (UC), accounts for around 20% of disease variance, highlighting the need to characterise environmental ... -
Autoimmunity to stromal-derived autoantigens in rheumatoid ectopic germinal centers exacerbates arthritis and impacts clinical response
(American Society for Clinical Investigation, 17-06-2024)Ectopic lymphoid structures (ELSs) in the rheumatoid synovial joints sustain autoreactivity against locally expressed autoantigens. We recently identified recombinant monoclonal antibodies (RA-rmAbs) derived from single, ... -
Multi-parameter phenotyping of platelets and characterisation of the effects of agonists using machine learning
(Elsevier, 22-07-2024)Platelet function is driven by the expression of specialised surface markers. The concept of distinct circulating sub-populations of platelets has emerged in recent years, but their exact nature remains debatable. Objective To ... -
Perinatal thymic-derived CD8alphabeta-expressing gammadelta T cells are innate interferon-gamma producers that expand in IL-7R/STAT5B-driven neoplasms
(Nature Research, 27-05-2024)The contribution of γδ T cells to immune responses is associated with rapid secretion of interferon-γ (IFN-γ). Here, we show a perinatal thymic wave of innate IFN-γ-producing γδ T cells that express CD8αβ heterodimers and ... -
Development of the Gastrointestinal Tract
(PMPH-USA, 2000)The authors chronicle the development of the gastrointestinal system b eginning with the embryology of the gastrointestinal tract through dev elopment of cells to hormones and enzymes. -
40th EASD Annual Meeting of the European Association for the Study of Diabetes
(2004-08)Abstracts from 40th EASD Annual Meeting of the European Association for the Study of Diabetes -
Erythromycin for prokinesis: imprudent prescribing?
(BioMed Central, 2005-12-19) -
Erythromycin for prokinesis: imprudent prescribing?
(BioMed Central, 2005-12-19)Problems with antibiotic resistant bacteria are increasing in the hospital and particularly in the intensive care unit. Methicillin-resistant Staphylococcus aureus, Acinetobacter baumanii and extended spectrum beta-lactamase ... -
Immunization with a lentiviral vector stimulates both CD4 and CD8 T cell responses to an ovalbumin transgene.
(2006-02)Lentiviral vectors encoding antigens are promising vaccine candidates because they transduce dendritic cells (DC) in vivo and prime CTL responses. Here we examine their stimulation of antigen-specific CD4(+) T cells, ... -
In-vitro activity of polymyxin B in combination with imipenem, rifampicin and azithromycin versus multidrug resistant strains of Acinetobacter baumannii producing OXA-23 carbapenemases.
(2006-04-21)BACKGROUND: Acinetobacter baumannii has emerged as a major nosocomial pathogen worldwide. Many of the circulating strains exhibit multi-drug resistance remaining consistently susceptible only to polymyxins. In-vitro studies ...
