Centre for Immunobiology: Recent submissions
Now showing items 281-300 of 1121
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Anti-interleukin-21 antibody and liraglutide for the preservation of β-cell function in adults with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled, phase 2 trial.
(2021-04)BACKGROUND: Type 1 diabetes is characterised by progressive loss of functional β-cell mass, necessitating insulin treatment. We aimed to investigate the hypothesis that combining anti-interleukin (IL)-21 antibody (for ... -
Exploring the Evidence for an Immunomodulatory Role of Vitamin D in Juvenile and Adult Rheumatic Disease
(Frontiers Media, 2021-02-18) -
Exploring a combined biomarker for tuberculosis treatment response: protocol for a prospective observational cohort study.
(BMJ, 2021-07-08)INTRODUCTION: An improved understanding of factors explaining tuberculosis (TB) treatment response is urgently needed to help clinicians optimise and personalise treatment and assist scientists undertaking novel treatment ... -
Intestinal Biopsies for the Evaluation of Environmental Enteropathy and Environmental Enteric Dysfunction.
(2021-07-17)Environmental enteric dysfunction (EED) is a syndrome characterised by impairments of digestion and absorption and intestinal barrier failure in people living in insanitary or tropical environments. There is substantial ... -
Contribution of Schistosoma mansoni to systemic inflammation and microbial translocation among people with HIV in Zambia.
(2021-07-14)BACKGROUND: Schistosoma mansoni is hyperendemic in many rural areas of Zambia where up to 77% of people are positive for infection via serologic evaluation. Zambia also has a high prevalence of HIV infection. Individually, ... -
14,17,18-Trihydroxy-Eicosatetraenoic Acid: A Novel Pro-Resolving Lipid Mediator from Marine Microalgae.
(2021-06-11)Specialized pro-resolving mediators (SPMs) are enzymatically oxygenated derivatives of polyunsaturated fatty acids that function as central immunoregulators in mammals. Among them are resolvins (Rvs) that stimulate the ... -
Platelets orchestrate the resolution of pulmonary inflammation in mice by T reg cell repositioning and macrophage education.
(2021-07-05)Beyond hemostasis, platelets actively participate in immune cell recruitment and host defense, yet their potential in the resolution of inflammatory processes remains unknown. Here, we demonstrate that platelets are recruited ... -
Constrained TCRγδ-associated Syk activity engages PI3K to facilitate thymic development of IL-17A–secreting γδ T cells
(American Association for the Advancement of Science, 2021-07-20) -
Rapid testing of gut permeability using oral fluorescein and confocal laser endomicroscopy in Zambian adults.
(2021-06-12)BACKGROUND: Dual sugar testing for gut permeability is time-consuming and complex. We explored the utility of fluorescein as a simple and inexpensive alternative method. METHODS: We used a confocal laser endomicroscopy ... -
Determinants of non-adherence to anti-TB treatment in high income, low TB incidence settings: a scoping review.
(International Union Against Tuberculosis and Lung Disease, 2021-06-01)BACKGROUND: Improving adherence to anti-TB treatment is a public health priority in high-income, low incidence (HILI) regions. We conducted a scoping review to identify reported determinants of non-adherence in HILI ... -
40th EASD Annual Meeting of the European Association for the Study of Diabetes
(2004-08)Abstracts from 40th EASD Annual Meeting of the European Association for the Study of Diabetes -
Cessation of ciprofloxacin prophylaxis in haemato-oncology patients at a London teaching hospital
(2021-04)This is the pre-peer reviewed version of the following article: (2021), Posters. Br J Haematol, 193: 77-232. https://doi.org/10.1111/bjh.17492, which has been published in final form at https://doi.org/10.1111/bjh.17492. ... -
An audit of fever-2-needle time in haemato-oncology patients during COVID-19.
(2021-04)This is the pre-peer reviewed version of the following article: (2021), Posters. Br J Haematol, 193: 77-232. https://doi.org/10.1111/bjh.17492, which has been published in final form at https://doi.org/10.1111/bjh.17492. ... -
Correction: Marked variability in bioactivity between commercially available bovine colostrum for human use; implications for clinical trials
(Public Library of Science, 2020-10-06) -
Peanut diversity and specific activity are the dominant IgE characteristics for effector cell activation in children.
(2021-03-03)BACKGROUND: IgE mediates allergic reactions to peanut; however, peanut-specific IgE (sIgE) levels do not always equate to clinical peanut allergy. Qualitative differences between sIgE of peanut sensitised but tolerant (PS) ...