Browsing Centre for Cell Biology and Cutaneous Research by Title
Now showing items 261-280 of 381
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Orchestrated control of filaggrin-actin scaffolds underpins cornification.
(2018-04-01)Epidermal stratification critically depends on keratinocyte differentiation and programmed death by cornification, leading to formation of a protective skin barrier. Cornification is dynamically controlled by the protein ... -
P2X7 in Cancer: From Molecular Mechanisms to Therapeutics
(2020-06-04) -
P33 Skinvaders: gamification of the skin barrier to engage school-age children in the biology of the skin
(Oxford University Press, 2024-05-17) -
Pachyonychia congenita - pathogenesis of pain and approaches to treatment.
(Oxford University Press, 2024-05-28)Pachyonychia congenita is an autosomal dominant genodermatosis characterized by a triad of chronic severe plantar pain, focal palmoplantar keratoderma, and hypertrophic nail dystrophy. Plantar pain can be debilitating and ... -
Pachyonychia Congenita: A Research Agenda Leading to New Therapeutic Approaches.
(2023-12-14)Pachyonychia congenita (PC) is a dominantly inherited genetic disorder of cornification. PC stands out among other genodermatoses because despite its rarity, it has been the focus of a very large number of pioneering ... -
Percutaneous collagen induction (microneedling) for the management of non-atrophic scars: literature review.
(2019-01)Introduction: Percutaneous collagen induction (PCI) or needling techniques are increasingly popular in the reconstructive and aesthetic arena. The underlying mechanisms of action rest on producing a pattern of non-ablative ... -
Persistent kallikrein 5 activation induces atopic dermatitis-like skin architecture independent of PAR2 activity.
(2017-11)BACKGROUND: Upregulation of kallikreins (KLKs) including KLK5 has been reported in atopic dermatitis (AD). KLK5 has biological functions that include degrading desmosomal proteins and inducing proinflammatory cytokine ...