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A critical role for the ATP-sensitive potassium channel subunit KIR6.1 in the control of cerebral blood flow.
(2018-06-04)
KIR6.1 (KCNJ8) is a subunit of ATP sensitive potassium channel (KATP) that plays an important role in the control of peripheral vascular tone and is highly expressed in brain contractile cells (vascular smooth muscle cells ...
Correction to: Minimum Quality Threshold in Pre-Clinical Sepsis Studies (MQTiPSS): an international expert consensus initiative for improvement of animal modeling in sepsis
(Springer Berlin Heidelberg, 2018-09-17)
Correction to: Infection
https://doi.org/10.1007/s15010-018-1183-8
The original version of this article unfortunately contained
mistakes.
The Tables 1–3 were missing. The correct versions of
Tables 1, 2 and 3 are given ...
Postmortem Genetic Testing for Cardiac Ion Channelopathies in Stillbirths.
(2018-01)
BACKGROUND: Although stillbirth is a significant health problem worldwide, the definitive cause of death remains elusive in many cases, despite detailed autopsy. In this study of partly explained and unexplained stillbirths, ...
NNT is a key regulator of adrenal redox homeostasis and steroidogenesis in male mice.
(2018-01)
Nicotinamide nucleotide transhydrogenase, NNT, is a ubiquitous protein of the inner mitochondrial membrane with a key role in mitochondrial redox balance. NNT produces high concentrations of NADPH for detoxification of ...
Utilization of data below the analytical limit of quantitation in pharmacokinetic analysis and modeling: promoting interdisciplinary debate.
(2018-08-01)
Traditionally, bioanalytical laboratories do not report actual concentrations for samples with results below the LOQ (BLQ) in pharmacokinetic studies. BLQ values are outside the method calibration range established during ...
Prospective association between handgrip strength and cardiac structure and function in UK adults.
(2018)
BACKGROUND: Handgrip strength, a measure of muscular fitness, is associated with cardiovascular (CV) events and CV mortality but its association with cardiac structure and function is unknown. The goal of this study was ...
Nicotinamide Nucleotide Transhydrogenase as a Novel Treatment Target in Adrenocortical Carcinoma.
(2018-08-01)
Adrenocortical carcinoma (ACC) is an aggressive malignancy with poor response to chemotherapy. In this study, we evaluated a potential new treatment target for ACC, focusing on the mitochondrial reduced form of NAD phosphate ...