Centre for Tumour Biology: Recent submissions
Now showing items 141-160 of 380
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CADM1 inhibits squamous cell carcinoma progression by reducing STAT3 activity.
(Springer Nature, 2016-04-01)Although squamous cell carcinomas (SqCCs) of the lungs, head and neck, oesophagus, and cervix account for up to 30% of cancer deaths, the mechanisms that regulate disease progression remain incompletely understood. Here, ... -
Generation of neighbor-labeling cells to study intercellular interactions in vivo.
(Springer Nature, 2020-12-11)Understanding cell-cell interactions is critical in most, if not all, research fields in biology. Nevertheless, studying intercellular crosstalk in vivo remains a relevant challenge, due mainly to the difficulty in spatially ... -
Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses
(2019-02-22)Converting carcinomas in benign oncocytomas has been suggested as a potential anti-cancerstrategy. One of the oncocytoma hallmarks is the lack of respiratory complex I (CI). Herewe use genetic ablation of this enzyme to ... -
Targeting FGFR signalling to disrupt cellular cross-talk in pancreatic cancer
(Elsevier, 2020-12-01) -
STARPAC clinical trial
(Elsevier, 2020-12) -
Chapter Eleven - Concurrent in situ analysis of point mutations and immune infiltrate in FFPE cancers
(Elsevier, 2020)Existing methodology for analysis of genetic heterogeneity generally involves digestion of the tumor tissue, followed by bulk DNA extraction or single cell preparation. Such methods destroy the tissue morphology, and ... -
Navigating the path to distant metastasis
(2020-07)