Browsing Centre for Tumour Biology by Subject "Membrane Proteins"

Now showing items 1-2 of 2

    • CADM1 inhibits squamous cell carcinoma progression by reducing STAT3 activity. 

      Vallath, S; Sage, EK; Kolluri, KK; Lourenco, SN; Teixeira, VS; Chimalapati, S; George, PJ; Janes, SM; Giangreco, A (Springer Nature, 2016-04-01)
      Although squamous cell carcinomas (SqCCs) of the lungs, head and neck, oesophagus, and cervix account for up to 30% of cancer deaths, the mechanisms that regulate disease progression remain incompletely understood. Here, ...

    • The Spectrin cytoskeleton regulates the Hippo signalling pathway. 

      Fletcher, GC; Elbediwy, A; Khanal, I; Ribeiro, PS; Tapon, N; Thompson, BJ (2015-04-01)
      The Spectrin cytoskeleton is known to be polarised in epithelial cells, yet its role remains poorly understood. Here, we show that the Spectrin cytoskeleton controls Hippo signalling. In the developing Drosophila wing and ...