Browsing Centre for Tumour Biology by Title
Now showing items 268-287 of 380
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PHLDA1 Mediates Drug Resistance in Receptor Tyrosine Kinase-Driven Cancer
(Elsevier/Science Direct, 2018-02-27)Development of resistance causes failure of drugs targeting receptor tyrosine kinase (RTK) networks and represents a critical challenge for precision medicine. Here, we show that PHLDA1 downregulation is critical to ... -
Predicting Colorectal Cancer Occurrence in IBD.
(MDPI, 2021-06-10)Patients with colonic inflammatory bowel disease (IBD) are at an increased risk of developing colorectal cancer (CRC), and are therefore enrolled into a surveillance programme aimed at detecting dysplasia or early cancer. ... -
Psychological distress in out-patients undergoing flexible cystoscopy for the investigation of bladder cancer
(2015-05-04)© British Association of Urological Surgeons 2014. Objectives: Flexible cystoscopy can cause patients significant psychological distress, especially when utilised in the diagnostic pathway for suspected bladder cancer. We ... -
Quantification of subclonal selection in cancer from bulk sequencing data
(2016-12-22)Recent studies have identified prevalent subclonal architectures within many cancer types. However, the temporal evolutionary dynamics that produce these subclonal architectures remain unknown. Here we measure evolutionary ...