Browsing Centre for Cancer & Inflammation by Title

3D approaches to model the tumour microenvironment of pancreatic cancer

Loessner, D; Tomás-Bort, E; Kieler, M; Sharma, S; Candido, J (Ivyspring International Publisher, 2020-04-06)

In tumor engineering, 3D approaches are used to model components of the tumor microenvironment and to test new treatments. Pancreatic cancers are a cancer of substantial unmet need and survival rates are lower compared to ...

A 3D tumor microenvironment regulates cell proliferation, peritoneal growth and expression patterns.

Loessner, D; Rockstroh, A; Shokoohmand, A; Holzapfel, BM; Wagner, F; Baldwin, J; Boxberg, M; Schmalfeldt, B; Lengyel, E; Clements, JA (2019-01)

Peritoneal invasion through the mesothelial cell layer is a hallmark of ovarian cancer metastasis. Using tissue engineering technologies, we recreated an ovarian tumor microenvironment replicating this aspect of disease ...

Accurate quantification of chromosomal lesions via short tandem repeat analysis using minimal amounts of DNA

Jann, J-C; Nowak, D; Nolte, F; Fey, S; Nowak, V; Oblaender, J; Pressler, J; Palme, I; Xanthopoulos, C; Fabarius, A (2017-09)

Adaptive Upregulation of EGFR Limits Attenuation of Tumor Growth by Neutralizing IL6 Antibodies, with Implications for Combined Therapy in Ovarian Cancer

Milagrel, CS; Gopinathanl, G; Everitt, G; Thompson, RG; Kulbel, H; Zhong, H; Hollingsworth, RE; Grose, R; Bowte, DDL; Hochhauserzl, D (2015-04-01)

Adipocytes disrupt the translational programme of acute lymphoblastic leukaemia to favour tumour survival and persistence

Patel, B

Augmented reality in liver surgery.

Acidi, B; Ghallab, M; Cotin, S; Vibert, E; Golse, N (2023-04)

INTRODUCTION: During an operation, augmented reality (AR) enables surgeons to enrich their vision of the operating field by means of digital imagery, particularly as regards tumors and anatomical structures. While in some ...

Author Correction: A guiding map for inflammation

Netea, MG; Balkwill, F; Chonchol, M; Cominelli, F; Donath, MY; Giamarellos-Bourboulis, EJ; Golenbock, D; Gresnigt, MS; Heneka, MT; Hoffman, HM (2021-02)

Correction to: Nature Immunology https://doi.org/10.1038/ni.3790, published online 19 July 2017.

beta(3)A-integrin downregulates the urokinase-type plasminogen activator receptor (u-PAR) through a PEA3/ets transcriptional silencing element in the u-PAR promoter

Hapke, S; Gawaz, M; Dehne, K; Kohler, J; Marshall, JF; Graeff, H; Schmitt, M; Reuning, U; Lengyel, E (2001-03)

Cancer glycan epitopes: biosynthesis, structure and function

Pearce, OMT (2018-09)

A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer

Berlato, C; Khan, MN; Schioppa, T; Thompson, R; Maniati, E; Montfort, A; Jangani, M; Canosa, M; Kulbe, H; Hagemann, UB (2017-03-01)

Cell cycle perturbations and apoptosis induced by isohomohalichondrin B (IHB), a natural marine compound

Bergamaschi, D; Ronzoni, S; Taverna, S; Faretta, M; De Feudis, P; Faircloth, G; Jimeno, J; Erba, E; D'Incalci, M (1999-01)

Cells are Us - combining research and public engagement

Balkwill, FR (2021-03-24)

Characterisation of the fumarate hydratase repertoire in Trypanosoma cruzi.

de Pádua, RAP; Kia, AM; Costa-Filho, AJ; Wilkinson, SR; Nonato, MC (2017-09)

Nifurtimox and benznidazole represent the only treatments options available targeting Chagas disease, the most important parasitic infection in the Americas. However, use of these is problematic as they are toxic and ...

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics

Naba, A; Pearce, OMT; Del Rosario, A; Ma, D; Ding, H; Rajeeve, V; Cutillas, PR; Balkwill, FR; Hynes, RO (2017-08)

The Chemokine CXCL10 is a Potential Regulator of Cancer Stem Cells in High Grade Serous Carcinoma

McDermott, JR; Jones, R; Lockley, M; Balkwill, FR (2017)

Chemotherapy Induces Tumor-Associated Macrophages that Aid Adaptive Immune Responses in Ovarian Cancer

Heath, O; Berlato, C; Maniati, E; Lakhani, A; Pegrum, C; Kotantaki, P; Elorbany, S; Bohm, S; Barry, ST; Annibaldi, A (2021)

Combining measures of immune infiltration shows additive effect on survival prediction in high-grade serous ovarian carcinoma

Montfort, A; Owen, S; Piskorz, AM; Supernat, A; Moore, L; Al-Khalidi, S; Bohm, S; Pharoah, P; McDermott, J; Balkwill, FR (2020-06-09)

A Comprehensive Epithelial Tubo-Ovarian Cancer Risk Prediction Model Incorporating Genetic and Epidemiological Risk Factors

Lee, A; Yang, X; Manchanda, R; Pharoah, PPD; Antoniou, AC

Consent for third molar tooth extractions in Australia and New Zealand: a review of current practice

Badenoch-Jones, EK; Lynham, AJ; Loessner, D (2016-06)

Critical questions in ovarian cancer research and treatment: Report of an American Association for Cancer Research Special Conference.

Bast, RC; Matulonis, UA; Sood, AK; Ahmed, AA; Amobi, AE; Balkwill, FR; Wielgos-Bonvallet, M; Bowtell, DDL; Brenton, JD; Brugge, JS (2019-06-15)

Substantial progress has been made in understanding ovarian cancer at the molecular and cellular level. Significant improvement in 5-year survival has been achieved through cytoreductive surgery, combination platinum-based ...