Browsing Centre for Cancer & Inflammation by Author "Maniati, E"
Now showing items 1-11 of 11
-
A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer
Berlato, C; Khan, MN; Schioppa, T; Thompson, R; Maniati, E; Montfort, A; Jangani, M; Canosa, M; Kulbe, H; Hagemann, UB (2017-03-01) -
Chemotherapy Induces Tumor-Associated Macrophages that Aid Adaptive Immune Responses in Ovarian Cancer
Heath, O; Berlato, C; Maniati, E; Lakhani, A; Pegrum, C; Kotantaki, P; Elorbany, S; Bohm, S; Barry, ST; Annibaldi, A (2021) -
Deconstruction of a Metastatic Tumor Microenvironment Reveals a Common Matrix Response in Human Cancers
Pearce, OMT; Delaine-Smith, RM; Maniati, E; Nichols, S; Wang, J; Bohm, S; Rajeeve, V; Ullah, D; Chakravarty, P; Jones, RR (2018-03) -
Discrepancies in the Tumor Microenvironment of Spontaneous and Orthotopic Murine Models of Pancreatic Cancer Uncover a New Immunostimulatory Phenotype for B Cells.
Spear, S; Candido, JB; McDermott, JR; Ghirelli, C; Maniati, E; Beers, SA; Balkwill, FR; Kocher, HM; Capasso, M (2019)B cells are salient features of pancreatic ductal adenocarcinoma (PDAC) tumors, yet their role in this disease remains controversial. Murine studies have indicated a protumoral role for B cells, whereas clinical data show ... -
A human multi-cellular model shows how platelets drive production of diseased extracellular matrix and tissue invasion
Malacrida, B; Nichols, S; Maniati, E; Jones, R; Delanie-Smith, R; Roozitalab, R; Tyler, EJ; Thomas, M; Boot, G; Mackerodt, J (2021-06-25) -
Modelling TGF beta R and Hh pathway regulation of prognostic matrisome molecules in ovarian cancer
Delaine-Smith, RM; Maniati, E; Malacrida, B; Nichols, S; Roozitalab, R; Jones, RR; Lecker, LSM; Pearce, OMT; Knight, MM; Balkwill, FR (Cell Press, 2021-05-29) -
Modelling TGFβR and Hh pathway regulation of prognostic matrisome molecules in ovarian cancer
Balkwill, F; Delaine-Smith, R; Maniati, E; Malacrida, B; Nichols, S; Roozitalab, R; Jones, R; LECKER, L; Pearce, O; Knight, M (Elsevier, 2021-05)In a multi-level ‘deconstruction’ of omental metastases, we previously identified a prognostic matrisome gene expression signature in high-grade serous ovarian cancer (HGSOC) and twelve other malignancies. Here, our aim ... -
Mouse Ovarian Cancer Models Recapitulate the Human Tumor Microenvironment and Patient Response to Treatment
Maniati, E; Berlato, C; Gopinathan, G; Heath, O; Kotantaki, P; Lakhani, A; McDermott, J; Pegrum, C; Delaine-Smith, RM; Pearce, OMT (2020-01-14) -
Mouse Ovarian Cancer Models Recapitulate the Human Tumor Microenvironment and Patient Response to Treatment
Maniati, E; Berlato, C; Gopinathan, G; Heath, O; Kotantaki, P; Lakhani, A; McDermott, J; Pegrum, C; Delaine-Smith, RM; Pearce, OMT -
A Strong B-cell Response Is Part of the Immune Landscape in Human High-Grade Serous Ovarian Metastases
Montfort, A; Pearce, O; Maniati, E; Vincent, BG; Bixby, L; Bohm, S; Dowe, T; Wilkes, EH; Chakravarty, P; Thompson, R (2017-01-01) -
TGFBI Production by Macrophages Contributes to an Immunosuppressive Microenvironment in Ovarian Cancer
Lecker, LSM; Berlato, C; Maniati, E; Delaine-Smith, R; Pearce, OMT; Heath, O; Nichols, SJ; Trevisan, C; Novak, M; McDermott, J (2021)