Browsing Barts Cancer Institute by Title
Now showing items 924-943 of 1165
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Resolving the fibrotic niche of human liver cirrhosis at single-cell level
(Springer Nature, 2019-11-21)Liver cirrhosis is a major cause of death worldwide and is characterized by extensive fibrosis. There are currently no effective antifibrotic therapies available. To obtain a better understanding of the cellular and molecular ... -
RESULTS OF INTENSIVE ALGORITHM-BASED SCREENING IN THE UK FAMILIAL OVARIAN CANCER SCREENING STUDY (UK FOCSS PHASE 2)
(ESGO and IGCS., 2013-10)Objectives To establish the performance of intensive screening for familial ovarian cancer using the risk of ovarian cancer algorithm (ROCA) and transvaginal sonogrpahy (TVS). Methods Between 14/06/2007 and 29/03/2012, ... -
Retinoic acid-responsive CD8 effector T-cells are selectively increased in IL-23-rich tissue in gastrointestinal GvHD.
(2020-09-09)Gastrointestinal (GI) graft-versus-host disease (GvHD) is a major barrier in allogeneic hematopoietic stem-cell transplantation (AHST). The metabolite retinoic acid (RA) potentiates GI-GvHD in mice via alloreactive T-cells ... -
Revising the Treatment Pathways in Lymphoma: New Standards of Care-How Do We Choose?
(2022-04)Diffuse large B-cell lymphoma and follicular lymphoma are the most commonly encountered non-Hodgkin lymphomas in clinical practice. Both are biologically heterogeneous, with management strategies that are becoming increasingly ... -
Réalité augmentée en chirurgie hépatique
(Elsevier, 2023-04) -
Risk of pancreatic cancer associated with family history of cancer and other medical conditions by accounting for smoking among relatives
(Oxford University Press, 2018-01-10)Background Family history (FH) of pancreatic cancer (PC) has been associated with an increased risk of PC, but little is known regarding the role of inherited/environmental factors or that of FH of other comorbidities in ... -
A risk prediction algorithm for ovarian cancer incorporating BRCA1, BRCA2, common alleles and other familial effects.
(2015-07)BACKGROUND: Although BRCA1 and BRCA2 mutations account for only ∼27% of the familial aggregation of ovarian cancer (OvC), no OvC risk prediction model currently exists that considers the effects of BRCA1, BRCA2 and other ... -
Risk Reducing Salpingectomy and Delayed Oophorectomy in high risk women: views of cancer geneticists, genetic counsellors and gynaecological oncologists in the UK
(Springer Verlag (Germany), 2015-07-16)Risk-reducing-salpingectomy and Delayed-Oophorectomy (RRSDO) is being proposed as a two-staged approach in place of RRSO to reduce the risks associated with premature menopause in high-risk women. We report on the ...