Rewiring mitochondrial pyruvate metabolism: switching off the light in cancer cells?
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Metabolic reprogramming is a characteristic of cancer cells. Three studies published in this month's Molecular Cell provide novel insights into the role of mitochondrial pyruvate in tumor metabolism and describe how targeting pyruvate transport and metabolism may afford therapeutic benefit.
AuthorsSzlosarek, PW; Lee, S; Pollard, PJ
- College Publications