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    RESULTS OF INTENSIVE ALGORITHM-BASED SCREENING IN THE UK FAMILIAL OVARIAN CANCER SCREENING STUDY (UK FOCSS PHASE 2) 
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    • RESULTS OF INTENSIVE ALGORITHM-BASED SCREENING IN THE UK FAMILIAL OVARIAN CANCER SCREENING STUDY (UK FOCSS PHASE 2)
    •   QMRO Home
    • Barts Cancer Institute
    • Centre for Experimental Cancer Medicine
    • RESULTS OF INTENSIVE ALGORITHM-BASED SCREENING IN THE UK FAMILIAL OVARIAN CANCER SCREENING STUDY (UK FOCSS PHASE 2)
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    RESULTS OF INTENSIVE ALGORITHM-BASED SCREENING IN THE UK FAMILIAL OVARIAN CANCER SCREENING STUDY (UK FOCSS PHASE 2)

    Volume
    23
    Publisher
    ESGO and IGCS.
    DOI
    10.1097/01.IGC.0000437414.49882.6a
    Journal
    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
    Issue
    8
    ISSN
    1048-891X
    Metadata
    Show full item record
    Abstract
    Objectives To establish the performance of intensive screening for familial ovarian cancer using the risk of ovarian cancer algorithm (ROCA) and transvaginal sonogrpahy (TVS). Methods Between 14/06/2007 and 29/03/2012, 4,531 women at an estimated ≥10% lifetime risk of OC/FTC were screened by 42 UK centres for 14,263 women screen years with 4-monthly CA125 analysed by the ROCA. TVS was annual but brought forward if ROCA results were non-normal. Women with suspicious scan and/or algorithm results were referred for possible surgical intervention. Participants were followed prospectively by centres, questionnaire and cancer registries. Data was censored 365 days after final screen, withdrawal or death.
    Authors
    Rosenthal, AN; Fraser, L; Philpott, S; Manchanda, R; Badman, P; Hadwin, R; Evans, DG; Eccles, D; Skates, S; Mackay, J
    URI
    https://qmro.qmul.ac.uk/xmlui/handle/123456789/56557
    Collections
    • Centre for Experimental Cancer Medicine [130]
    Licence information
    Unauthorized reproduction of this article is prohibited.
    Copyright statements
    2013 by ESGO and IGCS.
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