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Defective ATG16L1-mediated removal of IRE1 alpha drives Crohn's disease-like ileitis

dc.contributor.authorTschurtschenthaler, Men_US
dc.contributor.authorAdolph, TEen_US
dc.contributor.authorAshcroft, JWen_US
dc.contributor.authorNiederreiter, Len_US
dc.contributor.authorBharti, Ren_US
dc.contributor.authorSaveljeva, Sen_US
dc.contributor.authorBhattacharyya, Jen_US
dc.contributor.authorFlak, MBen_US
dc.contributor.authorShih, DQen_US
dc.contributor.authorFuhler, GMen_US
dc.contributor.authorParkes, Men_US
dc.contributor.authorKohno, Ken_US
dc.contributor.authorIwawaki, Ten_US
dc.contributor.authorvan der Woude, CJen_US
dc.contributor.authorHarding, HPen_US
dc.contributor.authorSmith, AMen_US
dc.contributor.authorPeppelenbosch, MPen_US
dc.contributor.authorTargan, SRen_US
dc.contributor.authorRon, Den_US
dc.contributor.authorRosenstiel, Pen_US
dc.contributor.authorBlumberg, RSen_US
dc.contributor.authorKaser, Aen_US
dc.date.accessioned2018-03-06T11:34:00Z
dc.date.available2016-12-07en_US
dc.date.issued2017-02en_US
dc.date.submitted2018-02-19T12:43:48.459Z
dc.identifier.issn0022-1007en_US
dc.identifier.other10.1084/jem.20160791
dc.identifier.urihttp://jem.rupress.org/content/early/2017/01/11/jem.20160791
dc.identifier.urihttp://qmro.qmul.ac.uk/xmlui/handle/123456789/34317
dc.descriptionThis article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license,en_US
dc.description.sponsorshipThis study was supported by the European Research Council under the European Community’s Seventh Framework Program (grant FP7/2007-2013)/ERC, agreement no. 260961 to A. Kaser and grant HORIZON2020/ERC, agreement no. 648889 to A. Kaser), the Wellcome Trust (Investigator Award 106260/Z/14/Z to A. Kaser and Principal Research Fellowship 2008/Z/16/Z to D. Ron), the Cambridge Biomedical Research Centre (A. Kaser), a Medical Research Council PhD for clinicians training fellowship (grant MR/N001893/1 to J. Bhattacharyya), fellowships from the European Crohn’s and Colitis Organization (M. Tschurtschenthaler and T.E. Adolph), the Research Training Group Genes, Environment, and Inflammation supported by the Deutsche Forschungsgemeinschaft (grant RTG 1743/1 to P. Rosenstiel), the SFB877 subproject B9 and CLVIII ExC 306 Inflammation at Interfaces (P. Rosenstiel), and the National Institutes of Health (grants DK044319, DK051362, DK053056, and DK088199 to the Harvard Digestive Diseases Center and grant DK0034854 to R.S. Blumberg).en_US
dc.format.extent401 - 422en_US
dc.language.isoenen_US
dc.relation.ispartofJOURNAL OF EXPERIMENTAL MEDICINEen_US
dc.rightsCC BY NC BY SA
dc.titleDefective ATG16L1-mediated removal of IRE1 alpha drives Crohn's disease-like ileitisen_US
dc.typeArticle
dc.rights.holder2017 The Authors.
dc.identifier.doi10.1084/jem.20160791en_US
pubs.author-urlhttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000394251400010&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=612ae0d773dcbdba3046f6df545e9f6aen_US
pubs.issue2en_US
pubs.notesNo embargoen_US
pubs.publication-statusPublisheden_US
pubs.volume214en_US


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