Centre for Translational Medicine & Therapeutics: Recent submissions
Now showing items 81-100 of 844
-
MYOCARDIAL ALTERATIONS FOLLOWING TRAUMATIC HAEMORRHAGIC INJURY.
(2023-05-29)BACKGROUND: Cardiac Dysfunction (CD) has emerged as a key contributor to delayed organ failure and late mortality in patients surviving the initial traumatic haemorrhagic response. Inflammatory processes are implicated in ... -
Hemoperfusion in Trauma.
(2023)Major trauma care has seen significant improvements in early mortality, reflecting improvements in prehospital techniques for hemorrhage control and speed of access to specialized trauma centers. However, many patients ... -
Arterial cannulation with ultrasound: clinical trial protocol for a randomised controlled trial comparing handheld ultrasound versus palpation technique for radial artery cannulation.
(2022-12)BACKGROUND: Early intraoperative hypotension is associated with acute kidney and myocardial injury in patients undergoing noncardiac surgery. Precise arterial blood pressure measurement before and during the induction of ... -
Biochemical estimation of muscle mass and unbiased assessment of kidney function using serum creatinine and cystatin-C: A prognostic validation study within UK Biobank
(Queen Mary University of London, 2023)Statistical Analysis Plan – A proposal for the biochemical estimation of muscle mass and the unbiased assessment of kidney function using serum creatinine and cystatin-C: A prognostic validation study within UK Biobank. -
Effect of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Initiation on Organ Support-Free Days in Patients Hospitalized With COVID-19: A Randomized Clinical Trial.
(2023-04-11)IMPORTANCE: Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19. OBJECTIVE: To determine whether angiotensin-converting enzyme (ACE) inhibitor or angiotensin ... -
C-type natriuretic peptide regulates metabolic homeostasis
(2023-01-31) -
Characterising biological mechanisms underlying ethnicity-associated outcomes in COVID-19 through biomarker trajectories: a multicentre registry analysis.
(2023-09)BACKGROUND: Differences in routinely collected biomarkers between ethnic groups could reflect dysregulated host responses to disease and to treatments, and be associated with excess morbidity and mortality in COVID-19. ...