Centre for Translational Medicine & Therapeutics: Recent submissions
Now showing items 61-80 of 844
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Cardiovascular impairment in Shiga-toxin-2-induced experimental hemolytic-uremic syndrome: a pilot study.
(2023)INTRODUCTION: Hemolytic-uremic syndrome (HUS) can occur as a systemic complication of infection with Shiga toxin (Stx)-producing Escherichia coli (STEC). Most well-known aspects of the pathophysiology are secondary to ... -
Research Priorities in Prehabilitation for Patients Undergoing Cancer Surgery: An International Delphi Study.
(2023-08-24)BACKGROUND: Recently, the number of prehabilitation trials has increased significantly. The identification of key research priorities is vital in guiding future research directions. Thus, the aim of this collaborative study ... -
Critical care and pandemic preparedness and response.
(2023-09-07)Critical care was established partially in response to a polio epidemic in the 1950s. In the intervening 70 yr, several epidemics and pandemics have placed critical care and allied services under extreme pressure. Pandemics ... -
P153 Rituximab and tocilizumab and their effect on lung disease progression in scleroderma: a retrospective cohort study at a single centre
(Oxford University Press (OUP), 2023-04-24) -
A Transcriptomic Approach to Understand Patient Susceptibility to Pneumonia After Abdominal Surgery.
(2023-07-27)OBJECTIVE: To describe immune-pathways and gene-networks altered following major-abdominal surgery and identify transcriptomic patterns associated with postoperative pneumonia. SUMMARY BACKGROUND DATA: Nosocomial infections ... -
Propensity score methods in observational research: brief review and guide for authors.
(2023-07-20)Causal inference in observational research requires a careful approach to adjustment for confounding. One such approach is the use of propensity score analyses. In this editorial, we focus on the role of propensity score-based ... -
ESAIC focused guideline for the use of cardiac biomarkers in perioperative risk evaluation.
(2023-06-02)BACKGROUND: In recent years, there has been increasing focus on the use of cardiac biomarkers in patients undergoing noncardiac surgery. AIMS: The aim of this focused guideline was to provide updated guidance regarding the ... -
Sepsis-associated acute kidney injury - treatment standard.
(2023-07-03)Sepsis is a host's deleterious response to infection, which could lead to life-threatening organ dysfunction. Sepsis-associated acute kidney injury (SA-AKI) is the most frequent organ dysfunction and is associated with ... -
Muscle Ultrasound Changes and Physical Function of Critically Ill Children: A Comparison of Rectus Femoris Cross-Sectional Area and Quadriceps Thickness Measurements.
(2023-06)UNLABELLED: Quadriceps thickness (QT) and rectus femoris cross-sectional area (RFCSA) are both used to evaluate muscle changes in critically ill children. However, their correlation and association with physical function ... -
Long-term healthcare use after postoperative complications: an analysis of linked primary and secondary care routine data.
(2023-09)BACKGROUND: Postoperative complications are associated with reduced long-term survival. We characterise healthcare use changes after sentinel postoperative complications. METHODS: We linked primary and secondary care records ... -
Responsiveness of Critically Ill Adults With Multimorbidity to Rehabilitation Interventions: A Patient-Level Meta-Analysis Using Individual Pooled Data From Four Randomized Trials.
(2023-05-29)OBJECTIVE: To explore if patient characteristics (pre-existing comorbidity, age, sex, and illness severity) modify the effect of physical rehabilitation (intervention vs control) for the coprimary outcomes health-related ...