Centre for Translational Medicine & Therapeutics: Recent submissions
Now showing items 281-300 of 844
-
Risk factors associated with mechanical ventilation, autonomic nervous dysfunction and physical outcome in Vietnamese adults with tetanus.
(BioMed Central, 2021-06-21)BACKGROUND: Tetanus remains common in many low- and middle-income countries, but as critical care services improve, mortality from tetanus is improving. Nevertheless, patients develop severe syndromes associated with ... -
Surgical activity in England and Wales during the COVID-19 pandemic: a nationwide observational cohort study.
(2021-06-17)BACKGROUND: A significant proportion of healthcare resource has been diverted to the care of those with COVID-19. This study reports the volume of surgical activity and the number of cancelled surgical procedures during ... -
Should nutritional therapy be modified to account for mitochondrial dysfunction in critical illness?
(2021-06-11)Metabolic dysfunction, and its associated muscle atrophy, remains the most common complication of critical care. At the centre of this is mitochondrial dysfunction, secondary to hypoxia and systemic inflammation. This leads ... -
Talking to multi-morbid patients about critical illness: an evolving conversation.
(2021-06-11)Conversations around critical illness outcomes and benefits from intensive care unit (ICU) treatment have begun to shift away from binary discussions on living versus dying. Increasingly, the reality of survival with ... -
Muscle weakness and wasting in pediatric critical illness
(AME, 2021-05-01) -
THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview.
(2017-12)The Concise Guide to PHARMACOLOGY 2017/18 is the third in this series of biennial publications. This version provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective ... -
Novel methods to identify and measure catabolism
(2021-05-10) -
Preoperative nasopharyngeal swab testing and postoperative pulmonary complications in patients undergoing elective surgery during the SARS-CoV-2 pandemic
(Oxford University Press, 2020-11-11) -
Effectiveness of a quality improvement collaborative in reducing time to surgery for patients requiring emergency cholecystectomy
(John Wiley & Sons Ltd., 2019-10-08)Background Acute gallstone disease is a high-volume emergency general surgery presentation with wide variations in the quality of care provided across the UK. This controlled cohort evaluation assessed whether participation ... -
Restrictive fluid management versus usual care in acute kidney injury (REVERSE-AKI): a pilot randomized controlled feasibility trial.
(2021-05-07)PURPOSE: We compared a restrictive fluid management strategy to usual care among critically ill patients with acute kidney injury (AKI) who had received initial fluid resuscitation. METHODS: This multicenter feasibility ... -
Fluid balance -adjusted creatinine in diagnosing Acute Kidney Injury in the critically ill.
(2021-05-07)BACKGROUND: Acute Kidney Injury (AKI) is often diagnosed based on plasma creatinine (Cr) only. Adjustment of Cr for cumulative fluid balance due to potential dilution of Cr and subsequently missed Cr-based diagnosis of AKI ... -
Postoperative acute kidney injury in adult non-cardiac surgery: joint consensus report of the Acute Disease Quality Initiative and PeriOperative Quality Initiative.
(2021-05-11)Postoperative acute kidney injury (PO-AKI) is a common complication of major surgery that is strongly associated with short-term surgical complications and long-term adverse outcomes, including increased risk of chronic ... -
The relationships between anesthesia
(2014-01-01)Introduction The impact of anesthetic depth on hemodynamics has always been suspected to be a potentially pivotal factor in determining perioperative outcome, albeit with little systematically garnered evidence to support ... -
Theatre efficiency: starting on time Reply
(2012-11) -
Abstracts
(2015-06)