Browsing Centre for Translational Medicine & Therapeutics by Subject "SASP"
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Human CD8+ EMRA T cells display a senescence-associated secretory phenotype regulated by p38 MAPK.
(2018-02)Cellular senescence is accompanied by a senescence-associated secretory phenotype (SASP). We show here that primary human senescent CD8+ T cells also display a SASP comprising chemokines, cytokines and extracellular matrix ...