Browsing Centre for Translational Medicine & Therapeutics by Title
Now showing items 507-526 of 844
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Natural history, trajectory, and management of mechanically ventilated COVID-19 patients in the United Kingdom.
(2021-05-11)PURPOSE: The trajectory of mechanically ventilated patients with coronavirus disease 2019 (COVID-19) is essential for clinical decisions, yet the focus so far has been on admission characteristics without consideration of ... -
Neuromodulation of innate immunity by remote ischaemic conditioning in humans: Experimental cross-over study.
(2021-10)Experimental animal studies on the mechanisms of remote ischaemic conditioning (RIC)-induced cardioprotection against ischaemia/reperfusion injury demonstrate involvement of both neuronal and humoral pathways. Autonomic ... -
NKG2C+CD57+ natural killer with senescent features cells are induced in cutaneous leishmaniasis and accumulate in patients with lesional healing impairment.
(2024-05-03)Natural killer (NK) cells include different subsets with diverse effector capacities that are poorly understood in the context of parasitic diseases. Here, we investigated inhibitory and activating receptor expression on ... -
NKX2-5 regulates vessel remodelling in scleroderma-associated pulmonary arterial hypertension.
(2024-04-23)NKX2-5 is a member of the homeobox-containing transcription factors critical in regulating tissue differentiation in development. Here, we report a role for NKX2-5 in vascular smooth muscle cell phenotypic modulation in ... -
Not all light transmission aggregation assays are created equal: qualitative differences between light transmission and 96-well plate aggregometry.
(2018-11)In this short article, submitted as part of the review on platelet function testing, we illustrate the quantitative and qualitative differences between classical light transmission aggregometry (LTA) and 96-well plate ... -
Novel methods to identify and measure catabolism
(2021-05-10)