Browsing Centre for Translational Medicine & Therapeutics by Title
Now showing items 211-230 of 842
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Defining fluid removal in the intensive care unit: A national and international survey of critical care practice.
(2017-11)Design and objectives: To identify and compare how intensive care unit specialists in the United Kingdom and Australia and New Zealand self-reportedly define, assess and manage fluid overload in critically ill patients ... -
Depth of Anesthesia and Postoperative Delirium
(American Medical Association (AMA), 2019-02-05)Despite advances in medical therapies, the demand for surgery is consistently increasing.1 Each year, more than 300 million surgical procedures are performed worldwide, involving an increasingly elderly patient population.2,3 ... -
Deserved attention for acute kidney injury after major trauma
(Springer Nature Switzerland AG. Part of Springer Nature., 2019-04-23)Dear Editor, The systematic review of acute kidney injury (AKI) after trauma by Søvik et al. [1] adds much-needed data on the incidence and outcomes of trauma-associated AKI. The authors reported a pooled incidence of ... -
Development and validation of a reinforcement learning algorithm to dynamically optimize mechanical ventilation in critical care.
(Nature Research, 2021-02-19)The aim of this work was to develop and evaluate the reinforcement learning algorithm VentAI, which is able to suggest a dynamically optimized mechanical ventilation regime for critically-ill patients. We built, validated ... -
Discontinuation vs. continuation of renin-angiotensin system inhibition before non-cardiac surgery: the SPACE trial.
(2023-11-07)BACKGROUND AND AIMS: Haemodynamic instability is associated with peri-operative myocardial injury, particularly in patients receiving renin-angiotensin system (RAS) inhibitors (angiotensin-converting-enzyme inhibitors/angiotensin ...