Browsing Centre for Translational Medicine & Therapeutics by Title
Now showing items 489-508 of 842
-
Mode of blood pressure monitoring and morbidity after noncardiac surgery: A prospective multicentre observational cohort study.
(2021-01-12)BACKGROUND: Control of blood pressure remains a key goal of peri-operative care, because hypotension is associated with adverse outcomes after surgery. OBJECTIVES: We explored whether increased vigilance afforded by ... -
Modified Artificial Bee Colony Based Feature Optimized Federated Learning for Heart Disease Diagnosis in Healthcare
(2022-12-01)Heart disease is one of the lethal diseases causing millions of fatalities every year. The Internet of Medical Things (IoMT) based healthcare effectively enables a reduction in death rate by early diagnosis and detection ... -
Mortality after surgery with SARS-CoV-2 infection in England: A population-wide epidemiological study
(2021-02-20)Objectives: To confirm the incidence of perioperative SARS-CoV-2 infection and associated mortality after surgery. Design and setting: Analysis of routine electronic health record data from National Health Service ... -
Mortality and major postoperative complications within 1 year after vascular surgery: a prospective cohort study.
(MPPL, 2024-01-02)INTRODUCTION: Patients undergoing vascular procedures are prone to developing postoperative complications affecting their short‑term mortality. Prospective reports describing the incidence of long‑term complications after ... -
Mortality of emergency general surgical patients and associations with hospital structures and processes.
(2016-01)BACKGROUND: Variations in patient outcomes between providers have been described for emergency admissions, including general surgery. The aim of this study was to investigate whether differences in modifiable hospital ... -
Multidrug resistance proteins preferentially regulate natriuretic peptide-driven cGMP signalling in the heart & vasculature.
(2021-06-15)BACKGROUND & PURPOSE: Cyclic-3',5'-guanosine monophosphate (cGMP) underpins the bioactivity of nitric oxide (NO) and natriuretic peptides and is key to cardiovascular homeostasis. Cyclic GMP-driven responses are terminated ... -
Multiplicity of Nitric Oxide and Natriuretic Peptide Signalling in Heart Failure.
(2019-07-24)Heart failure (HF) is a common consequence of several cardiovascular diseases, and is understood as a vicious cycle of cardiac and haemodynamic decline. The current inventory of treatments either alleviate the pathophysiological ... -
Muscle Ultrasound Changes and Physical Function of Critically Ill Children: A Comparison of Rectus Femoris Cross-Sectional Area and Quadriceps Thickness Measurements.
(2023-06)UNLABELLED: Quadriceps thickness (QT) and rectus femoris cross-sectional area (RFCSA) are both used to evaluate muscle changes in critically ill children. However, their correlation and association with physical function ... -
Muscle wasting in the critically ill patient: how to minimise subsequent disability.
(Mark Allen Healthcare, 2020-04-02)Muscle wasting in critically ill patients is the most common complication associated with critical care. It has significant effects on physical and psychological health, mortality and quality of life. It is most severe in ... -
Muscle weakness and wasting in pediatric critical illness
(AME, 2021-05-01) -
MYOCARDIAL ALTERATIONS FOLLOWING TRAUMATIC HAEMORRHAGIC INJURY.
(2023-05-29)BACKGROUND: Cardiac Dysfunction (CD) has emerged as a key contributor to delayed organ failure and late mortality in patients surviving the initial traumatic haemorrhagic response. Inflammatory processes are implicated in ... -
Myocardial Injury After Noncardiac Surgery (MINS) in Vascular Surgical Patients: A Prospective Observational Cohort Study.
(2018-08)OBJECTIVE: To determine the prognostic relevance, clinical characteristics, and 30-day outcomes associated with myocardial injury after noncardiac surgery (MINS) in vascular surgical patients. BACKGROUND: MINS has been ...