Browsing Centre for Translational Medicine & Therapeutics by Title
Now showing items 389-408 of 842
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Inflammasomes: a novel therapeutic target in pulmonary hypertension?
(2018-05-30)Pulmonary hypertension (PH) is a rare, progressive pulmonary vasculopathy characterized by increased mean pulmonary arterial pressure, pulmonary vascular remodelling and right ventricular failure. Current treatments are ... -
Inflammation and altered metabolism impede efficacy of functional electrical stimulation in critically ill patients.
(2023-11-06)BACKGROUND: Critically ill patients suffer from acute muscle wasting, which is associated with significant physical functional impairment. We describe data from nested muscle biopsy studies from two trials of functional ... -
Innovative Anti-Inflammatory and Pro-resolving Strategies for Pulmonary Hypertension: High Blood Pressure Research Council of Australia Award 2019.
(2021-09-27)Pulmonary hypertension is a rare, ostensibly incurable, and etiologically diverse disease with an unacceptably high 5-year mortality rate (≈50%), worse than many cancers. Irrespective of pathogenic origin, dysregulated ... -
Integration of the Duke Activity Status Index into preoperative risk evaluation: a multicentre prospective cohort study.
(2020-03)BACKGROUND: The Duke Activity Status Index (DASI) questionnaire might help incorporate self-reported functional capacity into preoperative risk assessment. Nonetheless, prognostically important thresholds in DASI scores ...