Browsing Centre for Biochemical Pharmacology by Title
Now showing items 182-201 of 333
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Leukocytes from obese individuals exhibit an impaired SPM signature.
(2019-06)Specialized proresolving mediators (SPMs) biosynthesized from docosahexaenoic acids (DHAs) including resolvins (Rvs), protectins, and maresins are potent endogenous autacoids that actively resolve inflammation, protect ... -
Ligand Bias and Its Association With Pro-resolving Actions of Melanocortin Drugs.
(2018)Resolution Pharmacology identifies drugs developed on the biology of the resolution phase of inflammation, the complex molecular and cellular network of events that ensure the tight temporal and spatial control on the ... -
Lipid Mediator Metabolomics Via LC-MS/MS Profiling and Analysis.
(2018)Solid-phase extraction coupled with liquid chromatography tandem mass spectrometry provides a robust and sensitive approach for the identification and quantitation of specialized pro-resolving mediators (lipoxins, resolvins, ... -
Lipid mediators in platelet concentrate and extracellular vesicles: Molecular mechanisms from membrane glycerophospholipids to bioactive molecules.
(2019-08)Platelets are collected for transfusion to patients with different haematological disorders, and for logistical reasons, platelets are stored as concentrates. Despite carefully controlled conditions, platelets become ... -
Lipid mediators of inflammation and Resolution in individuals with tuberculosis and tuberculosis-Diabetes.
(Elsevier, 2019-11-11)Individuals with concurrent tuberculosis (TB) and Type 2 diabetes (DM) have a higher risk of adverse outcomes. To better understand potential immunological differences, we utilized a comprehensive panel to characterize ... -
The long-term sequelae of COVID-19: an international consensus on research priorities for patients with pre-existing and new-onset airways disease.
(Elsevier, 2021-08-17)Persistent ill health after acute COVID-19-referred to as long COVID, the post-acute COVID-19 syndrome, or the post-COVID-19 condition-has emerged as a major concern. We undertook an international consensus exercise to ... -
The low-density lipoprotein receptor (LDL-R) is an immune-metabolic checkpoint during CD8 T Lymphocytes activation
(2021-08-01)Meeting abstract -
Macrophage AXL receptor tyrosine kinase inflames the heart after reperfused myocardial infarction.
(2021-02-02)Tyro3, AXL, and MerTK (TAM) receptors are activated in macrophages in response to tissue injury and as such have been proposed as therapeutic targets to promote inflammation resolution during sterile wound healing, including ... -
Magnetically responsive layer-by-layer microcapsules can be retained in cells and under flow conditions to promote local drug release without triggering ROS production.
(Royal Society of Chemistry, 2020-03-25)Nanoengineered vehicles have the potential to deliver cargo drugs directly to disease sites, but can potentially be cleared by immune system cells or lymphatic drainage. In this study we explore the use of magnetism to ... -
Massage-like stroking boosts the immune system in mice
(2015-06-05)