Browsing Centre for Biochemical Pharmacology by Title
Now showing items 54-73 of 332
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Classical Flt3L-dependent dendritic cells control immunity to protein vaccine
(Rockefeller University Press, 2014-08-25)<jats:p>DCs are critical for initiating immunity. The current paradigm in vaccine biology is that DCs migrating from peripheral tissue and classical lymphoid-resident DCs (cDCs) cooperate in the draining LNs to initiate ... -
Clinical characteristics with inflammation profiling of Long-COVID and association with one-year recovery following hospitalisation in the UK: a prospective observational study
(2021)<h4>Summary</h4> <h4>Background</h4> There are currently no effective pharmacological or non-pharmacological interventions for Long-COVID. To identify potential therapeutic targets, we focussed on previously described four ... -
Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial.
(Elsevier, 2021-05-14)BACKGROUND: Many patients with COVID-19 have been treated with plasma containing anti-SARS-CoV-2 antibodies. We aimed to evaluate the safety and efficacy of convalescent plasma therapy in patients admitted to hospital with ... -
Cross-Reactive SARS-CoV-2 Neutralizing Antibodies From Deep Mining of Early Patient Responses.
(Frontiers Media, 2021-06-15)Passive immunization using monoclonal antibodies will play a vital role in the fight against COVID-19. The recent emergence of viral variants with reduced sensitivity to some current antibodies and vaccines highlights the ... -
Curbing Inflammation through Endogenous Pathways: Focus on Melanocortin Peptides.
(2013)The resolution of inflammation is now known to be an active process, armed with a multitude of mediators both lipid and protein in nature. Melanocortins are peptides endowed with considerable promise with their proresolution ... -
Delayed-onset myocarditis following COVID-19.
(Elsevier, 2021-02-19) -
Demonstrating Interactions of Transcription Factors with DNA by Electrophoretic Mobility Shift Assay.
(2017)Confirming the binding of a transcription factor with a particular DNA sequence may be important in characterizing interactions with a synthetic promoter. Electrophoretic mobility shift assay is a powerful approach to ... -
Dendritic cells and adipose tissue.
(2016-12)Visceral adipose tissue inflammation in obesity is an established risk factor for metabolic syndrome, which can include insulin resistance, type 2 diabetes, hypertension and cardiovascular diseases. With obesity and related ...