Browsing Centre for Biochemical Pharmacology by Title
Now showing items 157-176 of 332
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The impact of environmental enrichment on the murine inflammatory immune response.
(2017-04-06)Living in a mentally and physically stimulating environment has been suggested to have a beneficial effect on the immune response. This study investigates these effects, utilizing a 2-week program of environmental enrichment ... -
Impact of Initiating Biologics in Patients With Severe Asthma on Long-Term Oral Corticosteroids or Frequent Rescue Steroids (GLITTER): Data From the International Severe Asthma Registry.
(2023-09)BACKGROUND: Effectiveness of biologics has neither been established in patients with high oral corticosteroid exposure (HOCS) nor been compared with effectiveness of continuing with HOCS alone. OBJECTIVE: To examine the ... -
The impact of the first COVID-19 surge on severe asthma patients in the UK. Which is worse: the virus or the lockdown?
(2021-01)Asthma therapy, including monoclonal antibodies, was not associated with #COVID19 infection or hospitalisation in a UK severe asthma population. Shielding led to a reported worsening of mental health in nearly half of ... -
Impaired Production and Diurnal Regulation of Vascular RvDn-3 DPA Increase Systemic Inflammation and Cardiovascular Disease.
(2018-03-16)RATIONALE: Diurnal mechanisms are central to regulating host responses. Recent studies uncovered a novel family of mediators termed as specialized proresolving mediators that terminate inflammation without interfering with ... -
Initial Considerations Before Designing a Promoter Construct.
(2017)Before designing a synthetic promoter, it can be helpful to think about its final application. Is the study purely an in vitro exercise in monitoring short-term promoter activity from an episomal vector, or does the promoter ... -
Innate and adaptive immunity in acute myocarditis.
(2024-06-01)Acute myocarditis is an acute inflammatory cardiomyopathy associated with cardiac damage triggered by a virus or a pathological immune activation. It may present with a wide range of clinical presentations, ranging from ... -
Interferon-gamma signs off an old heart.
(2023-10-26) -
International severe asthma registry (ISAR): protocol for a global registry
(BioMed Central, 2020-08-14)