Browsing Centre for Biochemical Pharmacology by Title
Now showing items 148-167 of 333
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Immune Regulatory Mediators in Plasma from Patients with Acute Decompensation are Associated With 3-month Mortality.
(2019-08-22)BACKGROUND & AIMS: Infection is a common cause of death in patients with cirrhosis. We investigated the association between the innate immune response and death within 3 months of hospitalization. METHODS: Plasma samples ... -
An immunologist's guide to CD31 function in T-cells
(2013-06-01) -
Immunometabolic Mechanisms of Heart Failure with Preserved Ejection Fraction.
(2022-03)Heart failure with preserved ejection fraction (HFpEF) is increasing in prevalence worldwide, already accounting for at least half of all heart failure (HF). As most patients with HFpEF are obese with metabolic syndrome, ... -
Immunoresolvents signaling molecules at intersection between the brain and immune system.
(2018-02)Understanding mechanisms that control immunity is central in the quest to gain insights into the etiopathology of many of the diseases that afflict modern societies. New results implicate the nervous system as a central ... -
Impact of comorbidities on EQ5D quality of life index in severe asthma
(Elsevier, 2024-05-31) -
The impact of environmental enrichment on the murine inflammatory immune response.
(2017-04-06)Living in a mentally and physically stimulating environment has been suggested to have a beneficial effect on the immune response. This study investigates these effects, utilizing a 2-week program of environmental enrichment ... -
Impact of Initiating Biologics in Patients With Severe Asthma on Long-Term Oral Corticosteroids or Frequent Rescue Steroids (GLITTER): Data From the International Severe Asthma Registry.
(2023-09)BACKGROUND: Effectiveness of biologics has neither been established in patients with high oral corticosteroid exposure (HOCS) nor been compared with effectiveness of continuing with HOCS alone. OBJECTIVE: To examine the ... -
The impact of the first COVID-19 surge on severe asthma patients in the UK. Which is worse: the virus or the lockdown?
(2021-01)Asthma therapy, including monoclonal antibodies, was not associated with #COVID19 infection or hospitalisation in a UK severe asthma population. Shielding led to a reported worsening of mental health in nearly half of ... -
Impaired Production and Diurnal Regulation of Vascular RvDn-3 DPA Increase Systemic Inflammation and Cardiovascular Disease.
(2018-03-16)RATIONALE: Diurnal mechanisms are central to regulating host responses. Recent studies uncovered a novel family of mediators termed as specialized proresolving mediators that terminate inflammation without interfering with ...