Browsing Centre for Biochemical Pharmacology by Title
Now showing items 117-136 of 332
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From Welfare to Warfare: The Arbitration of Host-Microbiota Interplay by the Type VI Secretion System.
(Frontiers Media, 2020)The health of mammals depends on a complex interplay with their microbial ecosystems. Compartments exposed to external environments such as the mucosal surfaces of the gastrointestinal tract accommodate the gut microbiota, ... -
The Glucose Transporter 2 regulates CD8+ T cell function via environment sensing
(Nature Research, 2023)T cell activation is associated with a profound and rapid metabolic response to meet increased energy demands for cell division, differentiation and development of effector function. Glucose uptake and engagement of the ... -
Human Sepsis Eicosanoid and Proresolving Lipid Mediator Temporal Profiles: Correlations With Survival and Clinical Outcomes.
(2017-01)OBJECTIVE: To identify and measure recently described chemical mediators, termed specialized pro-resolving mediators that actively regulate the resolution of acute-inflammation, and correlate measurements with clinical ... -
Hypercholesterolemia Impairs Clearance of Neutrophil Extracellular Traps and Promotes Inflammation and Atherosclerotic Plaque Progression.
(2021-08-05)OBJECTIVE: Hypercholesterolemia-induced NETosis and accumulation of neutrophil extracellular traps (NETs) in the atherosclerotic lesion exacerbates inflammation and is causally implicated in plaque progression. We investigated ...