Browsing Centre for Experimental Medicine and Rheumatology (EMR) by Subject "histamine"

Now showing items 1-3 of 3

    • Heterogeneity of Human Mast Cells With Respect to MRGPRX2 Receptor Expression and Function. 

      Varricchi, G; Pecoraro, A; Loffredo, S; Poto, R; Rivellese, F; Genovese, A; Marone, G; Spadaro, G (Frontiers Media SA, 2019-07-03)
      Mast cells and their mediators play a role in the control of homeostasis and in the pathogenesis of several disorders. The concept of rodent mast cell heterogeneity, initially established in the mid-1960s has been extended ...

    • Human mast cells and basophils-How are they similar how are they different? 

      Varricchi, G; Raap, U; Rivellese, F; Marone, G; Gibbs, BF (2018-03)
      Mast cells and basophils are key contributors to allergies and other inflammatory diseases since they are the most prominent source of histamine as well as numerous additional inflammatory mediators which drive inflammatory ...

    • Superantigenic Activation of Human Cardiac Mast Cells. 

      Varricchi, G; Loffredo, S; Borriello, F; Pecoraro, A; Rivellese, F; Genovese, A; Spadaro, G; Marone, G (MDPI, 2019-04-12)
      B cell superantigens, also called immunoglobulin superantigens, bind to the variable regions of either the heavy or light chain of immunoglobulins mirroring the lymphocyte-activating properties of classical T cell ...