Browsing Centre for Experimental Medicine and Rheumatology (EMR) by Subject "PTPN14"

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    • PTPN14 phosphatase and YAP promote TGFβ signalling in rheumatoid synoviocytes. 

      Bottini, A; Wu, DJ; Ai, R; Le Roux, M; Bartok, B; Bombardieri, M; Doody, KM; Zhang, V; Sacchetti, C; Zoccheddu, M (BMJ Publishing Group Ltd, 2019-02-26)
      OBJECTIVE: We aimed to understand the role of the tyrosine phosphatase PTPN14-which in cancer cells modulates the Hippo pathway by retaining YAP in the cytosol-in fibroblast-like synoviocytes (FLS) from patients with ...