Browsing Centre for Experimental Medicine and Rheumatology (EMR) by Author "Woollard, KJ"
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Integrin CD11b positively regulates TLR4-induced signalling pathways in dendritic cells but not in macrophages.
Ling, GS; Bennett, J; Woollard, KJ; Szajna, M; Fossati-Jimack, L; Taylor, PR; Scott, D; Franzoso, G; Cook, HT; Botto, M (Nature Research, 2014-01-15)Tuned and distinct responses of macrophages and dendritic cells to Toll-like receptor 4 (TLR4) activation induced by lipopolysaccharide (LPS) underpin the balance between innate and adaptive immunity. However, the molecule(s) ... -
Triglyceride-Rich Lipoproteins Modulate the Distribution and Extravasation of Ly6C/Gr1low Monocytes
Saja, MF; Baudino, L; Jackson, WD; Cook, HT; Malik, TH; Fossati-Jimack, L; Ruseva, M; Pickering, MC; Woollard, KJ; Botto, M (2015-09-22)Monocytes are heterogeneous effector cells involved in the maintenance and restoration of tissue integrity. However, their response to hyperlipidemia remains poorly understood. Here, we report that in the presence of ...