Browsing Centre for Experimental Medicine and Rheumatology (EMR) by Author "Valesini, G"
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Autophagy induces protein carbamylation in fibroblast-like synoviocytes from patients with rheumatoid arthritis.
Manganelli, V; Recalchi, S; Capozzi, A; Riitano, G; Mattei, V; Longo, A; Di Franco, M; Alessandri, C; Bombardieri, M; Valesini, G (Oxford University Press, 2018-11-01)Objectives: Autophagy is a homeostatic and physiological process that promotes the turnover of proteins and organelles damaged in conditions of cellular stress. We previously demonstrated that autophagy represents a key ... -
Guidelines for biomarkers in autoimmune rheumatic diseases - evidence based analysis.
Giacomelli, R; Afeltra, A; Alunno, A; Bartoloni-Bocci, E; Berardicurti, O; Bombardieri, M; Bortoluzzi, A; Caporali, R; Caso, F; Cervera, R (Elsevier B.V., 2019-01)Autoimmune rheumatic diseases are characterised by an abnormal immune system response, complement activation, cytokines dysregulation and inflammation. In last years, despite many progresses in managing these patients, it ... -
Reduction of autophagy and increase in apoptosis correlates with a favorable clinical outcome in patients with rheumatoid arthritis treated with anti-TNF drugs
Vomero, M; Manganelli, V; Barbati, C; Colasanti, T; Capozzi, A; Finucci, A; Spinelli, FR; Ceccarelli, F; Perricone, C; Truglia, S (BioMed Central, 2019-01-29)© 2019 The Author(s). Background: Autophagy has emerged as a key mechanism in the survival and function of T and B lymphocytes, and its activation was involved in apoptosis resistance in rheumatoid arthritis (RA). To ...