Browsing Centre for Experimental Medicine and Rheumatology (EMR) by Author "Sciacca, E"
Now showing items 1-20 of 21
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Axl and MerTK regulate synovial inflammation and are modulated by IL-6 inhibition in rheumatoid arthritis.
Nerviani, A; Boutet, M-A; Ghirardi, GM; Goldmann, K; Sciacca, E; Rivellese, F; Pontarini, E; Prediletto, E; Abatecola, F; Caliste, M (2024-03-16)The TAM tyrosine kinases, Axl and MerTK, play an important role in rheumatoid arthritis (RA). Here, using a unique synovial tissue bioresource of patients with RA matched for disease stage and treatment exposure, we assessed ... -
CELL LINEAGE-SPECIFIC TRANSCRIPT DECONVOLUTION OF SYNOVIAL BIOPSIES FROM THE R4RA TRIAL IDENTIFIES CELL POPULATIONS ASSOCIATED WITH RESPONSE TO RITUXIMAB AND TOCILIZUMAB
Rivellese, F; Cubuk, C; Surace, A; Goldmann, K; Sciacca, E; Giorli, G; Nerviani, A; Fossati-Jimack, L; Thorborn, G; Bombardieri, M (2022) -
CLINICAL RESPONSE TO RITUXIMAB IS ASSOCIATED WITH PREVENTION OF B-CELL DRIVEN SALIVARY GLAND INFLAMMATION AND EPITHELIAL RESTORATION AS REVEALED BY MOLECULAR PATHOLOGY: RESULTS FROM THE TRACTISS TRIAL IN PRIMARY SJOGREN'S SYNDROME
Pontarini, E; Chowdhury, F; Sciacca, E; Grigoriadou, S; Murray-Brown, W; Rivellese, F; Lucchesi, D; Goldmann, K; Fossati-Jimack, L; Jaworska, E (2022) -
DEGGs: an R package with shiny app for the identification of differentially expressed gene-gene interactions in high-throughput sequencing data
Sciacca, E; Alaimo, S; Silluzio, G; Ferro, A; Latora, V; Pitzalis, C; Pulvirenti, A; Lewis, MJ (2023) -
Demo Abstract an Ultrasonic Intra Body Area Network for Ehealth Applications
Galluccio, L; Milardo, S; Sciacca, E (2017-05-01) -
A Feasibility Analysis on the Use of Ultrasonic Multihop Communications for E-Health Applications
Galluccio, L; Milardo, S; Sciacca, E; International Conference on Communications (ICC) 2017 (2017-05-01) -
Harnessing gene-gene interactions via an RNA-Sequencing network analysis framework improves precision medicine prediction in rheumatoid arthritis
Sciacca, E; Surace, A; Alaimo, S; Pulvirenti, A; Rivellese, F; Goldmann, K; Ferro, A; Latora, V; Pitzalis, C; Lewis, M (2021) -
IN-DEPTH ANALYSIS OF AXL AND MERTK EXPRESSION PATTERNS AND REGULATION BY BIOLOGIC TREATMENTS IN RHEUMATOID ARTHRITIS
Nerviani, A; Boutet, MA; Ghirardi, GM; Goldmann, K; Sciacca, E; Rivellese, F; Pontarini, E; Caliste, M; Prediletto, E; Bombardieri, M (2022) -
INVOLVEMENT OF LARGE JOINTS AT DISEASE PRESENTATION IS ASSOCIATED WITH DIVERSE HISTOPATHOLOGICAL FEATURES AND CLINICAL OUTCOMES IN EARLY RHEUMATOID ARTHRITIS
Rivellese, F; Humby, F; Ribera, GL; Nerviani, A; Sciacca, E; Giorli, G; Hands, R; Fossati-Jimack, L; Thorborn, G; Lewis, M (BMJ, 2020-06)Abstract OP0217 from Annual European Congress of Rheumatology (EULAR), 2020. -
MICRO-RNA ENRICHED PATHWAY IMPACT ANALYSIS APPLIED TO SYNOVIAL RNA-SEQ IN EARLY RHEUMATOID ARTHRITIS IDENTIFIES RESPONSE PREDICTION PATHWAYS
Sciacca, E; Alaimo, S; Pulvirenti, A; Latora, V; Humby, F; Ferro, A; Lewis, MJ; Pitzalis, C (2020) -
Module Signatures of Synovial Single-cell States Identify Disease Phenotypes in Early Treatment-naive Rheumatoid Arthritis
Rivellese, F; Pontarini, E; Cubuk, C; Nerviani, A; Fossati-Jimack, L; Surace, A; Sciacca, E; Goldmann, K; Bombardieri, M; Lewis, M (2022) -
Novel Network Tool Highlights Key Features Associated with Disease Pathotypes and Response to Treatment in Early Rheumatoid Arthritis
Sciacca, E; Surace, A; Lewis, M; Alaimo, S; Latora, V; Rivellese, F; Pulvirenti, A; Ferro, A; Pitzalis, C (2020-10)Abstract Number: 0973 from ACR Convergence 2020 -
OP0136 RITUXIMAB PREVENTS THE PROGRESSION OF B-CELL DRIVEN INFLAMMATORY INFILTRATE IN THE MINOR SALIVARY GLANDS OF PRIMARY SJOGREN’S SYNDROME BY DOWNREGULATING IMMUNOLOGICAL PATHWAYS KEY IN ECTOPIC GERMINAL CENTRE ORGANIZATION: RESULTS FROM THE TRACTISS TRIAL
Pontarini, E; Chowdhury, F; Sciacca, E; Grigoriadou, S; Rivellese, F; Lucchesi, D; Goldmann, K; Fossati-Jimack, L; Emery, P; Ng, WF (2021-05-19) -
Recapitulating thyroid cancer histotypes through engineering embryonic stem cells
Veschi, V; Turdo, A; Modica, C; Verona, F; Di Franco, S; Gaggianesi, M; Tirro, E; Di Bella, S; Iacono, ML; Pantina, VD (2023) -
Rituximab Prevents the Progression of B-cell Driven Inflammatory Infiltrate in the Minor Salivary Glands of Primary Sjogren's Syndrome by Downregulating Immunological Pathways Key in Ectopic Germinal Centre Organization: Results from the TRACTISS Trial
Pontarini, E; Chowdhury, F; Sciacca, E; Grigoriadou, SA; Rivellese, F; Lucchesi, D; Goldmann, K; Fossati-Jimack, L; Emery, P; Ng, W-F (2021) -
RITUXIMAB PREVENTS WORSENING OF B-CELL DRIVEN SALIVARY GLAND INFLAMMATION AND EXCRETORY FUNCTION IN PRIMARY SJOGREN'S SYNDROME: RESULTS FROM THE TRACTISS TRIAL
Pontarini, E; Chowdhury, F; Sciacca, E; Grigoriadou, S; Emery, P; Ng, WF; Sutcliffe, N; Rivellese, F; Tappuni, A; Lucchesi, D (2022) -
Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial
Rivellese, F; Surace, AEA; Goldmann, K; Sciacca, E; cubuk, C; Giorli, G; John, CR; Nerviani, A; Fossati-Jimack, L; Thorborn, G (2022) -
Robustness of forensic speaker verification systems based on Alize/Lia_Ral toolkit
Bellomo, F; Beritelli, F; Sciacca, E (2014-10-01) -
Serum and tissue biomarkers associated with CRESS and STAR response to B-cell targeted therapy in TRACTISS trial of Sjogren's syndrome
Pontarini, E; Sciacca, E; Chowdhury, F; Grigoriadou, S; Rivellese, F; Murray-Brown, WJ; Lucchesi, D; Fossati-Jimack, L; Nerviani, A; Jaworska, E (Oxford University Press, 2023-12-10)OBJECTIVES: To identify peripheral and salivary gland (SG) biomarkers of response/resistance to B-cell depletion based on the novel concise CRESS (cCRESS) and candidate STAR composite endpoints. METHODS: Longitudinal ... -
SYNOVIAL RNA-SEQ ANALYSIS OF THE R4RA TRIAL IDENTIFIES SIGNATURES OF TREATMENT RESISTANCE AND REFRACTORY STATE IN RHEUMATOID ARTHRITIS
Surace, A; Sciacca, E; Goldmann, K; Rivellese, F; Cubuk, C; Giorli, G; Fossati-Jimack, L; Ahmed, M; Prediletto, E; Bombardieri, M (2022)