Browsing Centre for Experimental Medicine and Rheumatology (EMR) by Author "Proudman, SM"
Now showing items 1-2 of 2
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Immune checkpoint inhibitor PD-1 pathway is down-regulated in synovium at various stages of rheumatoid arthritis disease progression.
Guo, Y; Walsh, AM; Canavan, M; Wechalekar, MD; Cole, S; Yin, X; Scott, B; Loza, M; Orr, C; McGarry, T (Public Library of Science, 2018-02-28)Immune checkpoint blockade with therapeutic anti-cytotoxic T lymphocyte-associated antigen (CTLA)-4 (Ipilimumab) and anti-programmed death (PD)-1 (Nivolumab and Pembrolizumab) antibodies alone or in combination has shown ... -
Integrative analysis reveals CD38 as a therapeutic target for plasma cell-rich pre-disease and established rheumatoid arthritis and systemic lupus erythematosus
Cole, S; Walsh, A; Yin, X; Wechalekar, MD; Smith, MD; Proudman, SM; Veale, DJ; Fearon, U; Pitzalis, C; Humby, F (2018-05-02)