Browsing Centre for Experimental Medicine and Rheumatology (EMR) by Author "Prediletto, E"
Now showing items 1-20 of 22
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AB0062 ABUNDANCE AND ACTIVATION OF MEMORY B-CELLS CHARACTERIZE SYNOVITIS IN RHEUMATOID ARTHRITIS PATIENTS WITH EARLY TREATMENT RESPONSE
Khmelevskaya, A; Houtman, M; Buerki, K; Pauli, C; Rivellese, F; Prediletto, E; Pitzalis, C; Distler, O; Ciurea, A; Ospelt, C (BMJ, 2023-06) -
AB0340 MULTI-DRUG RESISTANT RA IS ASSOCIATED WITH HIGHER BASELINE DISEASE ACTIVITY, MULTI-MORBIDITY, AND LOWER QUALITY OF LIFE: ANALYSES FROM THE R4RA BIOPSY-DRIVEN CLINICAL TRIAL
Rivellese, F; Currado, D; Giorli, G; Prediletto, E; Nerviani, A; Khmelevskaya, A; Micheroli, R; Ospelt, C; Lewis, M; Bombardieri, M (BMJ, 2023-06) -
ACE2 at the centre of COVID-19 from paucisymptomatic infections to severe pneumonia
Rivellese, F; Prediletto, E (2020-06) -
Axl and MerTK regulate synovial inflammation and are modulated by IL-6 inhibition in rheumatoid arthritis.
Nerviani, A; Boutet, M-A; Ghirardi, GM; Goldmann, K; Sciacca, E; Rivellese, F; Pontarini, E; Prediletto, E; Abatecola, F; Caliste, M (2024-03-16)The TAM tyrosine kinases, Axl and MerTK, play an important role in rheumatoid arthritis (RA). Here, using a unique synovial tissue bioresource of patients with RA matched for disease stage and treatment exposure, we assessed ... -
CHARACTERIZATION OF HSP60, A STROMAL-DERIVED AUTOANTIGEN, RECOGNIZED BY RA SYNOVIAL RECOMBINANT MONOCLONAL ANTIBODIES
Corsiero, E; Caliste, M; Jagemann, L; Prediletto, E; Pitzalis, C; Bombardieri, M (2022) -
DENDRITIC CELL-DERIVED IL-27 REGULATES THE MAGNITUDE OF INDUCIBLE ECTOPIC GERMINAL CENTRES BUT FAILS TO DOWNMODULATE IL-17 PRODUCTION IN CD4 T CELLS FROM PATIENTS WITH SJOGREN'S SYNDROME
Lucchesi, D; Coleby, R; Pontarini, E; Prediletto, E; Hill, D; Soria, AD; Rivellese, F; Pitzalis, C; Jones, S; Jones, G (2019-06) -
Dynamic spectrum of ectopic lymphoid B cell activation and hypermutation in the RA synovium characterized by NR4A nuclear receptor expression
Meednu, N; Rangel-Moreno, J; Zhang, F; Escalera-Rivera, K; Corsiero, E; Prediletto, E; DiCarlo, E; Goodman, S; Donlin, LT; Raychauduri, S (2022) -
Follicular dendritic cell differentiation is associated with distinct synovial pathotype signatures in rheumatoid arthritis
El Shikh, MEM; El Sayed, R; Aly, NAR; Prediletto, E; Hands, R; Fossati-Jimack, L; Bombardieri, M; Lewis, MJ; Pitzalis, C (2022) -
IL-27 REGULATES THE MAGNITUDE OF ECTOPIC GERMINAL CENTRES IN EXPERIMENTAL SIALADENITIS BUT FAILS TO MODULATE IL-17 AND IFNG PRODUCTION IN CD4 T CELLS FROM PATIENTS WITH SJOGREN'S SYNDROME
Lucchesi, D; Coleby, R; Pontarini, E; Prediletto, E; Rivellese, F; Hill, D; Soria, AD; Jones, S; Humphreys, I; Sutcliffe, N (2020-04) -
Impaired IL‐27 Mediated Control of CD4+ T Cell Function Impacts on Ectopic Lymphoid Structure Formation in Patients with Sjögren's Syndrome
Lucchesi, D; Coleby, R; Pontarini, E; Prediletto, E; Rivellese, F; Hill, DG; Derrac Soria, A; Jones, SA; Humphreys, IR; Sutcliffe, N (Wiley, 2020-04-20)This is the pre-peer reviewed version of the following article: Lucchesi, D., Coleby, R., Pontarini, E., Prediletto, E., Rivellese, F., Hill, D.G., Derrac Soria, A., Jones, S.A., Humphreys, I.R., Sutcliffe, N., Tappuni, ... -
IN-DEPTH ANALYSIS OF AXL AND MERTK EXPRESSION PATTERNS AND REGULATION BY BIOLOGIC TREATMENTS IN RHEUMATOID ARTHRITIS
Nerviani, A; Boutet, MA; Ghirardi, GM; Goldmann, K; Sciacca, E; Rivellese, F; Pontarini, E; Caliste, M; Prediletto, E; Bombardieri, M (2022) -
Interleukin-36 family dysregulation drives joint inflammation and therapy response in psoriatic arthritis.
Boutet, M-A; Nerviani, A; Lliso-Ribera, G; Lucchesi, D; Prediletto, E; Ghirardi, GM; Goldmann, K; Lewis, M; Pitzalis, C (2020-04-01)OBJECTIVES: IL-36 agonists are pro-inflammatory cytokines involved in the pathogenesis of psoriasis. However, their role in the pathogenesis of arthritis and treatment response to DMARDs in PsA remains uncertain. Therefore, ... -
NETosis as Source of Autoantigens in Rheumatoid Arthritis
Corsiero, E; Pratesi, F; Prediletto, E; Bombardieri, M; Migliorini, P (2016-11-14) -
O31 IL-27 regulates the magnitude of ectopic germinal centres in experimental sialadenitis but fails to modulate IL-17 and IFNg production in CD4 T cells from patients with Sjögren's syndrome
Lucchesi, D; Coleby, R; Pontarini, E; Prediletto, E; Rivellese, F; Hill, D; Soria, AD; Jones, S; Humphreys, I; Sutcliffe, N (2020-04-01) -
RA SYNOVIAL RECOMBINANT MONOCLONAL ANTIBODIES FROM SINGLE B CELLS TARGET CITRULLINATED CALRETICULIN
Corsiero, E; Jagemann, L; Prediletto, E; Pitzalis, C; Bombardieri, M (2017-03-01)Meeting abstract 08.34 from 37th European Workshop on Rheumatology Research (EWRR) Athens, GREECE, MAR 02-04, 2017 -
Rheumatoid Synovial Fibroblasts Display Imprinted Memory of Their Synovial Endotype Which Can Be Plastically Modulated by B-cells Crosstalk
Prediletto, E; Cubuk, C; Pontarini, E; Rivellese, F; Nerviani, A; Lucchesi, D; Caliste, M; Corsiero, E; Ahmed, M; Hands, R (2022) -
RHEUMATOID SYNOVIAL FIBROBLASTS DISPLAY IMPRINTED MEMORY OF THEIR SYNOVIAL ENDOTYPE WHICH CAN BE PLASTICALLY MODULATED BY B-CELLS CROSSTALK
Prediletto, E; Cubuk, C; Pontarini, E; Rivellese, F; Nerviani, A; Lucchesi, D; Caliste, M; Corsiero, E; Hands, R; Lewis, M (2022) -
Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial
Rivellese, F; Surace, AEA; Goldmann, K; Sciacca, E; cubuk, C; Giorli, G; John, CR; Nerviani, A; Fossati-Jimack, L; Thorborn, G (2022) -
Single cell analysis of RA synovial B cells reveals a dynamic spectrum of ectopic lymphoid B cell activation and hypermutation characterized by NR4A nuclear receptor expression
Meednu, N; Rangel-Moreno, J; Zhang, F; Escalera-Rivera, K; Corsiero, E; Prediletto, E; DiCarlo, E; Goodman, S; Donlin, L; Raychauduri, S (2021-05-16)<h4>ABSTRACT</h4> Ectopic lymphoid structures (ELS) can develop in rheumatoid arthritis (RA) synovial tissue, but the precise pathways of B cell activation and selection are not well understood. Here, we identified a unique ... -
STROMAL B-CELL CROSSTALK PROMOTES THE ESTABLISHMENT OF SYNOVIAL B CELL NICHES THROUGH THE SELECTION, ACTIVATION OF NATURALLY OCCURRING EBV plus B CELLS
Caliste, M; Prediletto, E; Corsiero, E; Jagemann, L; Pitzalis, C; Bombardieri, M (2022)