Browsing Centre for Experimental Medicine and Rheumatology (EMR) by Author "Kang, JB"

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    • Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes. 

      Zhang, F; Jonsson, AH; Nathan, A; Millard, N; Curtis, M; Xiao, Q; Gutierrez-Arcelus, M; Apruzzese, W; Watts, GFM; Weisenfeld, D (2023-11)
      Rheumatoid arthritis is a prototypical autoimmune disease that causes joint inflammation and destruction1. There is currently no cure for rheumatoid arthritis, and the effectiveness of treatments varies across patients, ...

    • Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution. 

      Kang, JB; Shen, AZ; Gurajala, S; Nathan, A; Rumker, L; Aguiar, VRC; Valencia, C; Lagattuta, KA; Zhang, F; Jonsson, AH (2023-12)
      The human leukocyte antigen (HLA) locus plays a critical role in complex traits spanning autoimmune and infectious diseases, transplantation and cancer. While coding variation in HLA genes has been extensively documented, ...