Browsing Centre for Experimental Medicine and Rheumatology (EMR) by Author "Hands-Greenwood, R"
Now showing items 1-2 of 2
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Comparative analysis of late-stage rheumatoid arthritis and osteoarthritis reveals shared histopathological features.
Boutet, M-A; Nerviani, A; Fossati-Jimack, L; Hands-Greenwood, R; Ahmed, M; Rivellese, F; Pitzalis, C (2023-11-19)OBJECTIVES: Osteoarthritis (OA) is a debilitating and heterogeneous condition, characterized by various levels of articular cartilage degradation, osteophytes formation, and synovial inflammation. Multiple evidences suggest ... -
Stratification of biological therapies by pathobiology in biologic-naive patients with rheumatoid arthritis (STRAP and STRAP-EU): two parallel, open-label, biopsy-driven, randomised trials
Rivellese, F; Nerviani, A; Giorli, G; Warren, L; Jaworska, E; Bombardieri, M; Lewis, MJ; Humby, F; Pratt, AG; Filer, A (2023-11-01)Background: Despite highly effective targeted therapies for rheumatoid arthritis, about 40% of patients respond poorly, and predictive biomarkers for treatment choices are lacking. We did a biopsy-driven trial to compare ...