Browsing Centre for Experimental Medicine and Rheumatology (EMR) by Author "Barnes, MR"
Now showing items 1-10 of 10
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Corrigendum: The RA-MAP Consortium: a working model for academia-industry collaboration.
Cope, AP; Barnes, MR; Belson, A; Binks, M; Brockbank, S; Bonachela-Capdevila, F; Carini, C; Fisher, BA; Goodyear, CS; Emery, P (2018-01-24)This corrects the article DOI: 10.1038/nrrheum.2017.200. -
Interferon-alpha-mediated therapeutic resistance in early rheumatoid arthritis implicates epigenetic reprogramming
Cooles, FAH; Tarn, J; Lendrem, DW; Naamane, N; Lin, CMA; Millar, B; Maney, NJ; Anderson, AE; Thalayasingam, N; Diboll, J (2022) -
Investigation of genetically regulated gene expression and response to treatment in rheumatoid arthritis highlights an association between IL18RAP expression and treatment response.
Cherlin, S; Lewis, MJ; Plant, D; Nair, N; Goldmann, K; Tzanis, E; Barnes, MR; McKeigue, P; Barrett, JH; Pitzalis, C (2020-11)OBJECTIVES: In this study, we sought to investigate whether there was any association between genetically regulated gene expression (as predicted using various reference panels) and anti-tumour necrosis factor (anti-TNF) ... -
Molecular Portraits of Early Rheumatoid Arthritis Identify Clinical and Treatment Response Phenotypes
Lewis, MJ; Barnes, MR; Blighe, K; Goldmann, K; Rana, S; Hackney, JA; Ramamoorthi, N; John, CR; Watson, DS; Kummerfeld, SK (2019-08-27) -
nestedcv: an R package for fast implementation of nested cross-validation with embedded feature selection designed for transcriptomics and high-dimensional data.
Lewis, MJ; Spiliopoulou, A; Goldmann, K; Pitzalis, C; McKeigue, P; Barnes, MR (2023)MOTIVATION: Although machine learning models are commonly used in medical research, many analyses implement a simple partition into training data and hold-out test data, with cross-validation (CV) for tuning of model ... -
The RA-MAP Consortium: a working model for academia-industry collaboration
Cope, AP; Barnes, MR; Belson, A; Binks, M; Brockbank, S; Bonachela-Capdevila, F; Carini, C; Fisher, BA; Goodyear, CS; Emery, P (2018-01) -
RA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients
Isaacs, JD; Brockbank, S; Pedersen, AW; Hilkens, C; Anderson, A; Stocks, P; Lendrem, D; Tarn, J; Smith, GR; Allen, B (2022) -
Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial
Rivellese, F; Surace, AEA; Goldmann, K; Sciacca, E; cubuk, C; Giorli, G; John, CR; Nerviani, A; Fossati-Jimack, L; Thorborn, G (2022) -
RNA sequencing and machine learning as molecular scalpels
Lewis, MJ; Barnes, MR (2018-07) -
Spectrum: fast density-aware spectral clustering for single and multi-omic data
John, CR; Watson, D; Barnes, MR; Pitzalis, C; Lewis, MJ (Oxford University Press, 2019-09-10)Motivation Clustering patient omic data is integral to developing precision medicine because it allows the identification of disease subtypes. A current major challenge is the integration multi-omic data to identify a ...