dc.contributor.author | Vaezi, MF | en_US |
dc.contributor.author | Sifrim, D | en_US |
dc.date.accessioned | 2017-10-23T14:12:15Z | |
dc.date.available | 2017-07-10 | en_US |
dc.date.issued | 2018-01 | en_US |
dc.date.submitted | 2017-10-12T14:08:05.995Z | |
dc.identifier.uri | http://qmro.qmul.ac.uk/xmlui/handle/123456789/28274 | |
dc.description.abstract | A detailed critique of objective measurements of gastroesophageal reflux disease (GERD) would improve management of patients suspecting of having reflux, leading to rational selection of treatment and better outcomes. Many diagnostic tests for GERD have been developed over the past decades. We analyze their development, positive- and negative-predictive values, and ability to predict response to treatment. These features are important for development of medical, surgical, and endoscopic therapies for GERD. We discuss the value of available diagnostic tests and review their role in management of patients with persistent reflux symptoms despite adequate medical or surgical treatment. This is becoming a significant health economic problem, due to the widespread use of proton pump inhibitors. GERD is believed to cause nonesophageal symptoms, such as those provoked by ear, nose, throat, or respiratory disorders. We analyze the value of GERD diagnostic tests in evaluation of these troublesome, nonesophageal symptoms. | en_US |
dc.description.sponsorship | Dr. Vaezi has research grant from Sandhill Scientific Inc. (Denver, Co, USA). Dr. Sifrim has research grants from Sandhill Scientific (Denver USA) and Reckitt Benckiser (Hull, UK) | en_US |
dc.format.extent | 289 - 301 | en_US |
dc.language | eng | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | Gastroenterology | en_US |
dc.rights | © 2017. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.subject | GERD | en_US |
dc.subject | Mucosal Impedance | en_US |
dc.subject | Reflux Monitoring | en_US |
dc.subject | Barium Sulfate | en_US |
dc.subject | Biopsy | en_US |
dc.subject | Chest Pain | en_US |
dc.subject | Contrast Media | en_US |
dc.subject | Diagnostic Techniques, Digestive System | en_US |
dc.subject | Esophagoscopy | en_US |
dc.subject | Esophagus | en_US |
dc.subject | Fluoroscopy | en_US |
dc.subject | Gastroesophageal Reflux | en_US |
dc.subject | Heartburn | en_US |
dc.subject | Humans | en_US |
dc.subject | Narrow Band Imaging | en_US |
dc.subject | Pepsin A | en_US |
dc.subject | Predictive Value of Tests | en_US |
dc.subject | Proton Pump Inhibitors | en_US |
dc.subject | Saliva | en_US |
dc.subject | Sensitivity and Specificity | en_US |
dc.subject | Surveys and Questionnaires | en_US |
dc.title | Assessing Old and New Diagnostic Tests for Gastroesophageal Reflux Disease. | en_US |
dc.type | Article | |
dc.rights.holder | © 2017 by the AGA Institute | |
dc.identifier.doi | 10.1053/j.gastro.2017.07.040 | en_US |
pubs.author-url | https://www.ncbi.nlm.nih.gov/pubmed/28774844 | en_US |
pubs.issue | 2 | en_US |
pubs.notes | Not known | en_US |
pubs.publication-status | Published | en_US |
pubs.volume | 154 | en_US |
dcterms.dateAccepted | 2017-07-10 | en_US |